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Research library: Membrane receptors/Ligands

2008: | December | November | October | September | August | July | June | May | April | March | February | January

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article
Toll-like receptor–induced arginase 1 in macrophages thwarts effective immunity against intracellular pathogens
Karim C El Kasmi et al.
Nature Immunology 9, 1399–1406
(December 2008); doi:10.1038/ni.1671
| Summary | Full Text (HTML / PDF) |

article
FGF acts as a co-transmitter through adenosine A2A receptor to regulate synaptic plasticity
Marc Flajolet et al.
Nature Neuroscience 11, 1402–1409
(December 2008); doi:10.1038/nn.2216
| Summary | Full Text (HTML / PDF) |

article
Micropatterning for quantitative analysis of protein-protein interactions in living cells
Michaela Schwarzenbacher et al.
Nature Methods 5, 1053–1060
(December 2008); doi:10.1038/nmeth.1268
| Summary | Full Text (HTML / PDF) |

letter
Deletion of vascular endothelial growth factor in myeloid cells accelerates tumorigenesis
Christian Stockmann et al.
Nature 456, 814–818
(11 December 2008); doi:10.1038/nature07445
| Summary | Full Text (HTML / PDF) |

article
Proteolytic cleavage in an endolysosomal compartment is required for activation of Toll-like receptor 9
Boyoun Park et al.
Nature Immunology 9, 1407–1414
(December 2008); doi:10.1038/ni.1669
| Summary | Full Text (HTML / PDF) |

review
Viral evasion and subversion of pattern-recognition receptor signalling
Andrew G. Bowie & Leonie Unterholzner
Nature Reviews Immunology 8, 911–922
(December 2008); doi:10.1038/nri2436
| Summary | Full Text (HTML / PDF) |

article
Treatment of inflammatory and neuropathic pain by uncoupling Src from the NMDA receptor complex
Xue Jun Liu et al.
Nature Medicine 14, 1325–1332
(December 2008); doi:10.1038/nm.1883
| Summary | Full Text (HTML / PDF) |

news and views
Breaking the pain connection
Catherine J Pallen
Nature Medicine 14, 1313–1315
(December 2008); doi:10.1038/nm1208-1313
| Full Text (HTML / PDF) |

review
FLT1 and its ligands VEGFB and PlGF: drug targets for anti-angiogenic therapy?
Christian Fischer, Massimiliano Mazzone, Bart Jonckx & Peter Carmeliet
Nature Reviews Cancer 8, 942–956
(December 2008); doi:10.1038/nrc2524
| Summary | Full Text (HTML / PDF) |

letter
The ectodomain of Toll-like receptor 9 is cleaved to generate a functional receptor
Sarah E. Ewald et al.
Nature 456, 658–662
(04 December 2008); doi:10.1038/nature07405
| Summary | Full Text (HTML / PDF) |

article
Tonic B cell antigen receptor signals supply an NF-κB substrate for prosurvival BLyS signaling
Jason E Stadanlick et al.
Nature Immunology 9, 1379–1387
(December 2008); doi:10.1038/ni.1666
| Summary | Full Text (HTML / PDF) |

review
Insulin and insulin-like growth factor signalling in neoplasia
Michael Pollak
Nature Reviews Cancer 8, 915–928
(December 2008); doi:10.1038/nrc2536
| Summary | Full Text (HTML / PDF) |

review
Mammalian glycosylation in immunity
Jamey D. Marth & Prabhjit K. Grewal
Nature Reviews Immunology 8, 874–887
(November 2008); doi:10.1038/nri2417
| Summary | Full Text (HTML / PDF) |

review
Cross-regulation between herpesviruses and the TNF superfamily members
John R. Šedý, Patricia G. Spear & Carl F. Ware
Nature Reviews Immunology 8, 861–873
(November 2008); doi:10.1038/nri2434
| Summary | Full Text (HTML / PDF) |

article
CEACAM1 inhibits Toll-like receptor 2–triggered antibacterial responses of human pulmonary epithelial cells
Hortense Slevogt et al.
Nature Immunology 9, 1270–1278
(November 2008); doi:10.1038/ni.1661
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article
Triggering the succinate receptor GPR91 on dendritic cells enhances immunity
Tina Rubic et al.
Nature Immunology 9, 1261–1269
(November 2008); doi:10.1038/ni.1657
| Summary | Full Text (HTML / PDF) |

perspective
VEGF-A splicing: the key to anti-angiogenic therapeutics?
Steven J. Harper & David O. Bates
Nature Reviews Cancer 8, 880–887
(November 2008); doi:10.1038/nrc2505
| Summary | Full Text (HTML / PDF) |

review
Silent synapses and the emergence of a postsynaptic mechanism for LTP
Geoffrey A. Kerchner & Roger A. Nicoll
Nature Reviews Neuroscience 9, 813–825
(November 2008); doi:10.1038/nrn2501
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review
The alliance of sphingosine-1-phosphate and its receptors in immunity
Juan Rivera, Richard L. Proia & Ana Olivera
Nature Reviews Immunology 8, 753–763
(October 2008); doi:10.1038/nri2400
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article
Mincle is an ITAM-coupled activating receptor that senses damaged cells
Sho Yamasaki, Eri Ishikawa, Machie Sakuma, Hiromitsu Hara, Koji Ogata & Takashi Saito
Nature Immunology 9, 1179–1188
(October 2008); doi:10.1038/ni.1651
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news and views
Sensing necrosis with Mincle
Gordon D Brown
Nature Immunology 9, 1099–1100
(October 2008); doi:10.1038/ni1008-1099
| Full Text (HTML / PDF) |

article
Mapping a molecular link between allosteric inhibition and activation of the glycine receptor
Paul S Miller, Maya Topf & Trevor G Smart
Nature Structural & Molecular Biology 15, 1084–1093
(October 2008); doi:10.1038/nsmb.1492
| Summary | Full Text (HTML / PDF) |

article
Toll-like receptor—mediated induction of type I interferon in plasmacytoid dendritic cells requires the rapamycin-sensitive PI(3)K-mTOR-p70S6K pathway
Weiping Cao et al.
Nature Immunology 9, 1157–1164
(October 2008); doi:10.1038/ni.1645
| Summary | Full Text (HTML / PDF) |

news and views
RAPping production of type I interferon in pDCs through mTOR
Mauro Costa-Mattioli & Nahum Sonenberg
Nature Immunology 9, 1097–1099
(October 2008); doi:10.1038/ni1008-1097
| Full Text (HTML / PDF) |

article
SAP-controlled T–B cell interactions underlie germinal centre formation
Hai Qi, Jennifer L. Cannons, Frederick Klauschen, Pamela L. Schwartzberg & Ronald N. Germain
Nature 455, 764–769
(9 October 2008); doi:10.1038/nature07345
| Summary | Full Text (HTML / PDF) |

news and views
Immunology: Helpful T cells are sticky
Elissa K. Deenick & Stuart G. Tangye
Nature 455, 745–747
(9 October 2008); doi:10.1038/455745a
| Full Text (HTML / PDF) |

letter
The type I TGF-β receptor engages TRAF6 to activate TAK1 in a receptor kinase-independent manner
Alessandro Sorrentino et al.
Nature Cell Biology 10, 1199–1207
(October 2008); doi:10.1038/ncb1780
| Summary | Full Text (HTML / PDF) |

perspective
A signal-switch hypothesis for cross-regulation of cytokine and TLR signalling pathways
Lionel B. Ivashkiv
Nature Reviews Immunology 8, 816–822
(October 2008); doi:10.1038/nri2396
| Summary | Full Text (HTML / PDF) |

review
The insulin paradox: aging, proteotoxicity and neurodegeneration
Ehud Cohen & Andrew Dillin
Nature Reviews Neuroscience 9, 759–767
(October 2008); doi:10.1038/nrn2474
| Summary | Full Text (HTML / PDF) |

review
Tailoring T-cell receptor signals by proximal negative feedback mechanisms
Oreste Acuto, Vincenzo Di Bartolo & Frédérique Michel
Nature Reviews Immunology 8, 699–712
(September 2008); doi:10.1038/nri2397
| Summary | Full Text (HTML / PDF) |

article
Prefrontal cortex AMPA receptor plasticity is crucial for cue-induced relapse to heroin-seeking
Michel C Van den Oever et al.
Nature Neuroscience 11, 1053–1058
(September 2008); doi:10.1038/nn.2165
| Summary | Full Text (HTML / PDF) |

review
Molecular mechanisms of L-DOPA-induced dyskinesia
Peter Jenner
Nature Reviews Neuroscience 9, 665–677
(September 2008); doi:10.1038/nrn2471
| Summary | Full Text (HTML / PDF) |

letter
Platelet-derived growth factor-α receptor activation is required for human cytomegalovirus infection
Liliana Soroceanu, Armin Akhavan & Charles S. Cobbs
Nature 455, 391–395
(18 September 2008); doi:10.1038/nature07209
| Summary | Full Text (HTML / PDF) |

article
Human microRNAs regulate stress-induced immune responses mediated by the receptor NKG2D
Noam Stern-Ginossar et al.
Nature Immunology 9, 1065–1073
(September 2008); doi:10.1038/ni.1642
| Summary | Full Text (HTML / PDF) |

news and views
Regulation of NKG2D ligands: a purposeful but delicate affair
Thomas Spies
Nature Immunology 9, 1013–1015
(September 2008); doi:10.1038/ni0908-1013
| Full Text (HTML / PDF) |

review
Adenosine receptors: therapeutic aspects for inflammatory and immune diseases
György Haskó, Joel Linden, Bruce Cronstein & Pál Pacher
Nature Reviews Drug Discovery 7, 759–770
(September 2008); doi:10.1038/nrd2638
| Summary | Full Text (HTML / PDF) |

article
Function of TRADD in tumor necrosis factor receptor 1 signaling and in TRIF-dependent inflammatory responses
Maria A Ermolaeva et al.
Nature Immunology 9, 1037–1046
(September 2008); doi:10.1038/ni.1638
| Summary | Full Text (HTML / PDF) |

article
The function of TRADD in signaling through tumor necrosis factor receptor 1 and TRIF-dependent Toll-like receptors
Yelena L Pobezinskaya et al.
Nature Immunology 9, 1047–1054
(September 2008); doi:10.1038/ni.1639
| Summary | Full Text (HTML / PDF) |

news and views
A birthday gift for TRADD
Gioacchino Natoli & Liv M I Austenaa
Nature Immunology 9, 1015–1016
(September 2008); doi:10.1038/ni0908-1015
| Full Text (HTML / PDF) |

article
The kinases MSK1 and MSK2 act as negative regulators of Toll-like receptor signaling
Olga Ananieva et al.
Nature Immunology 9, 1028–1036
(September 2008); doi:10.1038/ni.1644
| Summary | Full Text (HTML / PDF) |

article
A critical function for CD200 in lung immune homeostasis and the severity of influenza infection
Robert J Snelgrove et al.
Nature Immunology 9, 1074–1083
(September 2008); doi:10.1038/ni.1637
| Summary | Full Text (HTML / PDF) |

news and views
The CD200-CD200R axis in local control of lung inflammation
Patrick G Holt & Deborah H Strickland
Nature Immunology 9, 1011–1013
(September 2008); doi:10.1038/ni0908-1011
| Full Text (HTML / PDF) |

article
Serine phosphorylation of ephrinB2 regulates trafficking of synaptic AMPA receptors
Clara L Essmann et al.
Nature Neuroscience 11, 1035–1043
(September 2008); doi:10.1038/nn.2171
| Summary | Full Text (HTML / PDF) |

article
Actin restricts FcεRI diffusion and facilitates antigen-induced receptor immobilization
Nicholas L. Andrews et al.
Nature Cell Biology 10, 955–963
(August 2008); doi:10.1038/ncb1755
| Summary | Full Text (HTML / PDF) |

letter
Angiotensin receptor agonistic autoantibodies induce pre-eclampsia in pregnant mice
Cissy C Zhou et al.
Nature Medicine 14, 855–862
(August 2008); doi:10.1038/nm.1856
| Summary | Full Text (HTML / PDF) |

review
Pseudoreceptor models in drug design: bridging ligand- and receptor-based virtual screening
Yusuf Tanrikulu & Gisbert Schneider
Nature Reviews Drug Discovery 7, 667–677
(August 2008); doi:10.1038/nrd2615
| Summary | Full Text (HTML / PDF) |

review
The semaphorins: versatile regulators of tumour progression and tumour angiogenesis
Gera Neufeld & Ofra Kessler
Nature Reviews Cancer 8, 632–645
(August 2008); doi:10.1038/nrc2404
| Summary | Full Text (HTML / PDF) |

brief communication
The stress hormone corticosterone conditions AMPAR surface trafficking and synaptic potentiation
Laurent Groc, Daniel Choquet & Francis Chaouloff
Nature Neuroscience 11, 868–870
(August 2008); doi:10.1038/nn.2150
| Summary | Full Text (HTML / PDF) |

article
EGFR signalling as a negative regulator of Notch1 gene transcription and function in proliferating keratinocytes and cancer
Vihren Kolev et al.
Nature Cell Biology 10, 902–911
(August 2008); doi:10.1038/ncb1750
| Summary | Full Text (HTML / PDF) |

perspective
Regulation of TNFR1 and CD95 signalling by receptor compartmentalization
Stefan Schütze, Vladimir Tchikov & Wulf Schneider-Brachert
Nature Reviews Molecular Cell Biology 9, 655–662
(August 2008); doi:10.1038/nrm2430
| Summary | Full Text (HTML / PDF) |

article
PICK1 uncoupling from mGluR7a causes absence-like seizures
Federica Bertaso et al.
Nature Neuroscience 11, 940–948
(August 2008); doi:10.1038/nn.2142
| Summary | Full Text (HTML / PDF) |

letter
Crystal structure of the neurotrophin-3 and p75NTR symmetrical complex
Yong Gong, Peng Cao, Hong-jun Yu & Tao Jiang
Nature 454, 789–793
(7 August 2008); doi:10.1038/nature07089
| Summary | Full Text (HTML / PDF) |

review
Plasmacytoid dendritic cells: sensing nucleic acids in viral infection and autoimmune diseases
Michel Gilliet, Wei Cao & Yong-Jun Liu
Nature Reviews Immunology 8, 594–606
(August 2008); doi:10.1038/nri2358
| Summary | Full Text (HTML / PDF) |

article
Detection of heteromerization of more than two proteins by sequential BRET–FRET
Paulina Carriba et al.
Nature Methods 5, 727–733
(August 2008); doi:10.1038/nmeth.1229
| Summary | Full Text (HTML / PDF) |

letter
Blocking VEGFR-3 suppresses angiogenic sprouting and vascular network formation
Tuomas Tammela et al.
Nature 454, 656–660
(31 July 2008); doi:10.1038/nature07083
| Summary | Full Text (HTML / PDF) |

article
An essential function for β-arrestin 2 in the inhibitory signaling of natural killer cells
Ming-Can Yu et al.
Nature Immunology 9, 898–907
(August 2008); doi:10.1038/ni.1635
| Summary | Full Text (HTML / PDF) |

news and views
Arrestin NK cell cytotoxicity
Yenan T Bryceson & Hans-Gustaf Ljunggren
Nature Immunology 9, 835–836
(August 2008); doi:10.1038/ni0808-835
| Full Text (HTML / PDF) |

article
Structure of and influence of a tick complement inhibitor on human complement component 5
Folmer Fredslund et al.
Nature Immunology 9, 753–760
(July 2008); doi:10.1038/ni.1625
| Summary | Full Text (HTML / PDF) |

article
Regulation of humoral and cellular gut immunity by lamina propria dendritic cells expressing Toll-like receptor 5
Satoshi Uematsu et al.
Nature Immunology 9, 769–776
(July 2008); doi:10.1038/ni.1622
| Summary | Full Text (HTML / PDF) |

article
Rapid and modifiable neurotransmitter receptor dynamics at a neuronal synapse in vivo
Corey M McCann, Juan Carlos Tapia, Han Kim, Jay S Coggan & Jeff W Lichtman
Nature Neuroscience 11, 807–815
doi:10.1038/nn.2145
| Summary | Full Text (HTML / PDF) |

brief communication
A second binding site for double-stranded RNA in TLR3 and consequences for interferon activation
Nina Pirher, Karolina Ivičak, Jelka Pohar, Mojca Benčina & Roman Jerala
Nature Structural & Molecular Biology 15, 761–763
(July 2008); doi:10.1038/nsmb.1453
| Summary | Full Text (HTML / PDF) |

review
How regulatory T cells work
Dario A. A. Vignali, Lauren W. Collison & Creg J. Workman
Nature Reviews Immunology 8, 523–532
(July 2008); doi:10.1038/nri2343
| Summary | Full Text (HTML / PDF) |

article
The binding sites for cocaine and dopamine in the dopamine transporter overlap
Thijs Beuming et al.
Nature Neuroscience 11, 780–789
doi:10.1038/nn.2146
| Summary | Full Text (HTML / PDF) |

article
An autonomous CDR3δ is sufficient for recognition of the nonclassical MHC class I molecules T10 and T22 by γδ T cells
Erin J Adams, Pavel Strop, Sunny Shin, Yueh-Hsiu Chien & K Christopher Garcia
Nature Immunology 9, 777–784
(July 2008); doi:10.1038/ni.1620
| Summary | Full Text (HTML / PDF) |

review
Purinergic signalling and disorders of the central nervous system
Geoffrey Burnstock
Nature Reviews Drug Discovery 7, 575–590
(July 2008); doi:10.1038/nrd2605
| Summary | Full Text (HTML / PDF) |

review
Colony-stimulating factors in inflammation and autoimmunity
John A. Hamilton
Nature Reviews Immunology 8, 533–544
(July 2008); doi:10.1038/nri2356
| Summary | Full Text (HTML / PDF) |

letter
Structural basis for EGFR ligand sequestration by Argos
Daryl E. Klein, Steven E. Stayrook, Fumin Shi, Kartik Narayan & Mark A. Lemmon
Nature 453, 1271–1275
(26 June 2008); doi:10.1038/nature06978
| Summary | Full Text (HTML / PDF) |

article
A critical function for TGF-β signaling in the development of natural CD4+CD25+Foxp3+ regulatory T cells
Yongzhong Liu et al.
Nature Immunology 9, 632–640
(June 2008); doi:10.1038/ni.1607
| Summary | Full Text (HTML / PDF) |

article
The differentiation of human TH-17 cells requires transforming growth factor-β and induction of the nuclear receptor RORγt
Nicolas Manel, Derya Unutmaz & Dan R Littman
Nature Immunology 9, 641–649
(June 2008); doi:10.1038/ni.1610
| Summary | Full Text (HTML / PDF) |

article
A critical function for transforming growth factor-β, interleukin 23 and proinflammatory cytokines in driving and modulating human TH-17 responses
Elisabetta Volpe et al.
Nature Immunology 9, 650–657
(June 2008); doi:10.1038/ni.1613
| Summary | Full Text (HTML / PDF) |

news and views
Differentiation of human TH-17 cells does require TGF-β!
Anne O'Garra, Brigitta Stockinger & Marc Veldhoen
Nature Immunology 9, 588–590
(June 2008); doi:10.1038/ni0608-588
| Full Text (HTML / PDF) |

article
Persistent activation of an innate immune response translates respiratory viral infection into chronic lung disease
Edy Y Kim et al.
Nature Medicine 14, 633–640
(June 2008); doi:10.1038/nm1770
| Summary | Full Text (HTML / PDF) |

news and views
Lung NKT cell commotion takes your breath away
Sebastian Joyce & Luc Van Kaer
Nature Medicine 14, 609–610
(June 2008); doi:10.1038/nm0608-609
| Full Text (HTML / PDF) |

review
Neuregulin 1 in neural development, synaptic plasticity and schizophrenia
Lin Mei & Wen-Cheng Xiong
Nature Reviews Neuroscience 9, 437–452
(June 2008); doi:10.1038/nrn2392
| Summary | Full Text (HTML / PDF) |

article
The type I TGF-β receptor is covalently modified and regulated by sumoylation
Jong Seok Kang, Elise F. Saunier, Rosemary J. Akhurst & Rik Derynck
Nature Cell Biology 10, 654–664
(June 2008); doi:10.1038/ncb1728
| Summary | Full Text (HTML / PDF) |

news and views
SUMO amplifies TGF-β signalling
Kohei Miyazono, Yuto Kamiya & Keiji Miyazawa
Nature Cell Biology 10, 635–637
(June 2008); doi:10.1038/ncb0608-635
| Full Text (HTML / PDF) |

article
Scalable signaling mediated by T cell antigen receptor-CD3 ITAMs ensures effective negative selection and prevents autoimmunity
Jeff Holst et al.
Nature Immunology 9, 658–666
(June 2008); doi:10.1038/ni.1611
| Summary | Full Text (HTML / PDF) |

news and views
CD3 ITAMs count!
Bernard Malissen
Nature Immunology 9, 583–584
(June 2008); doi:10.1038/ni0608-583
| Full Text (HTML / PDF) |

article
Developmental axon pruning mediated by BDNF-p75NTR-dependent axon degeneration
Karun K Singh et al.
Nature Neuroscience 11, 649–658
(June 2008); doi:10.1038/nn.2114
| Summary | Full Text (HTML / PDF) |

news and views
Neurotrophins giveth and they taketh away
Alun M Davies
Nature Neuroscience 11, 627–628
(June 2008); doi:10.1038/nn0608-627
| Full Text (HTML / PDF) |

review
Drug development of MET inhibitors: targeting oncogene addiction and expedience
Paolo M. Comoglio, Silvia Giordano & Livio Trusolino
Nature Reviews Drug Discovery 7, 504–516
(June 2008); doi:10.1038/nrd2530
| Summary | Full Text (HTML / PDF) |

article
Structural basis of Nipah and Hendra virus attachment to their cell-surface receptor ephrin-B2
Thomas A Bowden et al.
Nature Structural & Molecular Biology 15, 567–572
(June 2008); doi:10.1038/nsmb.1435
| Summary | Full Text (HTML / PDF) |

news and views
Evil versus 'eph-ective' use of ephrin-B2
Benhur Lee, Zeynep Akyol Ataman & Lei Jin
Nature Structural & Molecular Biology 15, 540–542
(June 2008); doi:10.1038/nsmb0608-540
| Full Text (HTML / PDF) |

letter
An agonist-induced conformational change in the growth hormone receptor determines the choice of signalling pathway
Scott W. Rowlinson et al.
Nature Cell Biology 10, 740–747
(June 2008); doi:10.1038/ncb1737
| Summary | Full Text (HTML / PDF) |

article
Activity-dependent site-specific changes of glutamate receptor composition in vivo
Andreas Schmid et al.
Nature Neuroscience 11, 659–666
(June 2008); doi:10.1038/nn.2122
| Summary | Full Text (HTML / PDF) |

review
Presynaptic glutamate receptors: physiological functions and mechanisms of action
Paulo S. Pinheiro & Christophe Mulle
Nature Reviews Neuroscience 11, 423–436
(June 2008); doi:10.1038/nrn2379
| Summary | Full Text (HTML / PDF) |

article
Cell-surface protein-protein interaction analysis with time-resolved FRET and snap-tag technologies: application to GPCR oligomerization
Damien Maurel et al.
Nature Methods 5, 561–567
(June 2008); doi:10.1038/nmeth.1213
| Summary | Full Text (HTML / PDF) |

article
Sequential control of Toll-like receptor–dependent responses by IRAK1 and IRAK2
Tatsukata Kawagoe et al.
Nature Immunology 9, 684–691
(June 2008); doi:10.1038/ni.1606
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news and views
IRAK2 takes its place in TLR signaling
Etienne Meylan & Jürg Tschopp
Nature Immunology 9, 581–582
(June 2008); doi:10.1038/ni0608-581
| Full Text (HTML / PDF) |

review
Neuregulin 1 in neural development, synaptic plasticity and schizophrenia
Lin Mei & Wen-Cheng Xiong
Nature Reviews Neuroscience 9, 437–452
(June 2008); doi:10.1038/nrn2392
| Summary | Full Text (HTML / PDF) |

article
The proline-rich sequence of CD3ε controls T cell antigen receptor expression on and signaling potency in preselection CD4+CD8+ thymocytes
Michaël Mingueneau et al.
Nature Immunology 9, 522–532
(May 2008); doi:10.1038/ni.1608
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news and views
CD3ε: PeRuSing for positive selection
Jonathan S Maltzman & Gary A Koretzky
Nature Immunology 9, 457–459
(May 2008); doi:10.1038/ni0508-457
| Full Text (HTML / PDF) |

review
Immunobiology of the TAM receptors
Greg Lemke & Carla V. Rothline
Nature Reviews Immunology 8, 327–336
(May 2008); doi:10.1038/nri2303
| Summary | Full Text (HTML / PDF) |

article
Activation of c-Kit in dendritic cells regulates T helper cell differentiation and allergic asthma
Nandini Krishnamoorthy et al.
Nature Medicine 14, 565–573
(May 2008); doi:10.1038/nm1766
| Summary | Full Text (HTML / PDF) |

news and views
Dust mites' dirty dealings with dendritic cells
Dean Sheppard
Nature Medicine 14, 487–488
(May 2008); doi:10.1038/nm0508-487
| Summary | Full Text (HTML / PDF) |

review
Up on the tightrope: natural killer cell activation and inhibition
Lewis L Lanier
Nature Immunology 9, 495–502
(May 2008); doi:10.1038/ni1581
| Summary | Full Text (HTML / PDF) |

article
Functional roles for C5a receptors in sepsis
Daniel Rittirsch et al.
Nature Medicine 14, 551–557
(May 2008); doi:10.1038/nm1753
| Summary | Full Text (HTML / PDF) |

perspective
Not always the bad guys: B cells as regulators of autoimmune pathology
Simon Fillatreau, David Gray & Stephen M. Anderton
Nature Reviews Immunology 8, 391–397
(May 2008); doi:10.1038/nri2315
| Summary | Full Text (HTML / PDF) |

letter
Intercellular transfer of the oncogenic receptor EGFRvIII by microvesicles derived from tumour cells
Khalid Al-Nedawi et al.
Nature Cell Biology 10, 619–624
(May 2008); doi:10.1038/ncb1725
| Summary | Full Text (HTML / PDF) |

review
CCR7 and its ligands: balancing immunity and tolerance
Reinhold Förster, Ana Clara Davalos-Misslitz & Antal Rot
Nature Reviews Immunology 8, 362–371
(May 2008); doi:10.1038/nri2297
| Summary | Full Text (HTML / PDF) |

review
General anaesthesia: from molecular targets to neuronal pathways of sleep and arousal
Nicholas P. Franks
Nature Reviews Neuroscience 9, 370–386
(May 2008); doi:10.1038/nrn2372
| Summary | Full Text (HTML / PDF) |

review
The TWEAK–Fn14 cytokine–receptor axis: discovery, biology and therapeutic targeting
Jeffrey A. Winkles
Nature Reviews Drug Discovery 7, 411–425
(May 2008); doi:10.1038/nrd2488
| Summary | Full Text (HTML / PDF) |

article
TRIM30α negatively regulates TLR-mediated NF-κB activation by targeting TAB2 and TAB3 for degradation
Mude Shi et al.
Nature Immunology 9, 369–377
(April 2008); doi:10.1038/ni1577
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news and views
TRIM-ing down Tolls
Andrew G Bowie
Nature Immunology 9, 348–350
(April 2008); doi:10.1038/ni0408-348
| Full Text (HTML / PDF) |

article
Subversion of Toll-like receptor signaling by a unique family of bacterial Toll/interleukin-1 receptor domain-containing proteins
Christine Cirl et al.
Nature Medicine 14, 399–406
(April 2008); doi:10.1038/nm1734
| Summary | Full Text (HTML / PDF) |

news and views
Bacteria fight back against Toll-like receptors
Luke A J O'Neill
Nature Medicine 14, 370–372
(April 2008); doi:10.1038/nm0408-370
| Summary | Full Text (HTML / PDF) |

review
Structural diversity of G protein-coupled receptors and significance for drug discovery
Malin C. Lagerström & Helgi B. Schiöth
Nature Reviews Drug Discovery 7, 339–357
(April 2008); doi:10.1038/nrd2518
| Summary | Full Text (HTML / PDF) |

brief communication
Crystal structures of two human vitronectin, urokinase and urokinase receptor complexes
Qing Huai et al.
Nature Structural & Molecular Biology 15, 422–423
(April 2008); doi:10.1038/nsmb.1404
| Summary | Full Text (HTML / PDF) |

letter
Retinotopic order in the absence of axon competition
Nathan J. Gosse, Linda M. Nevin & Herwig Baier
Nature 452, 892–895
(17 April 2008); doi:10.1038/nature06816
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review
Cis interactions of immunoreceptors with MHC and non-MHC ligands
Werner Held & Roy A. Mariuzza
Nature Reviews Immunology 8, 269–278
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A common neurobiology for pain and pleasure
Siri Leknes & Irene Tracey
Nature Reviews Neuroscience 9, 314–320
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TRAM couples endocytosis of Toll-like receptor 4 to the induction of interferon-β
Jonathan C Kagan, Tian Su, Tiffany Horng, Amy Chow, Shizuo Akira & Ruslan Medzhitov
Nature Immunology 9, 361–368
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Location, location, location: identifying the neighborhoods of LPS signaling
Colin Watts
Nature Immunology 9, 343–345
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Plexin-A2 and its ligand, Sema6A, control nucleus–centrosome coupling in migrating granule cells
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Nature Neuroscience 11, 440–449
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Sequence- and target-independent angiogenesis suppression by siRNA via TLR3
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Nature 452, 591–597
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RNA interference: Generic block on angiogenesis
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Nature 452, 543–545
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Dendritic cell PAR1–S1P3 signalling couples coagulation and inflammation
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Nature 452, 654–658
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Synaptic NMDA receptor activity boosts intrinsic antioxidant defenses
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Nature Neuroscience 11, 476–487
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NMDA receptor activity regulates transcription of antioxidant pathways
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Nature Neuroscience 11, 381–382
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Identification of small molecules rescuing fragile X syndrome phenotypes in Drosophila
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Nature Chemical Biology 4, 256–263
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Regulation of VEGF-mediated angiogenesis by the Akt/PKB substrate Girdin
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Nature Cell Biology 10, 329–337
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IgE in allergy and asthma today
Hannah J. Gould & Brian J. Sutton
Nature Reviews Immunology 8, 205–217
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G protein-coupled receptor P2Y5 and its ligand LPA are involved in maintenance of human hair growth
Sandra M Pasternack et al.
Nature Genetics 40, 329–334
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Disruption of P2RY5, an orphan G protein-coupled receptor, underlies autosomal recessive woolly hair
Yutaka Shimomura et al.
Nature Genetics 40, 335–339
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Disentangling the roots of inherited hair disorders
Eli Sprecher
Nature Genetics 40, 265–266
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Toll-like receptors — taking an evolutionary approach
François Leulier & Bruno Lemaitre
Nature Reviews Genetics 9, 165–178
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CaMKII: a biochemical bridge linking accumbens dopamine and glutamate systems in cocaine seeking
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Nature Neuroscience 11, 344–353
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Thyrotrophin in the pars tuberalis triggers photoperiodic response
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Nature 452, 317–322
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Physiology: Brain comes to light
Hitoshi Okamura
Nature 452, 294–295
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HIV-1 envelope protein binds to and signals through integrin α4β7, the gut mucosal homing receptor for peripheral T cells
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Nature Immunology 9, 301–309
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HIV's gut feeling
Quentin Sattentau
Nature Immunology 9, 225–227
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MicroRNA Mirn140 modulates Pdgf signaling during palatogenesis
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Nature Genetics 40, 290–298
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MicroRNAs in facial development
David E Clouthier
Nature Genetics 40, 268–269
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Modulation of GABAA receptor desensitization uncouples sleep onset and maintenance in Drosophila
Jose Agosto, James C Choi, Katherine M Parisky, Geoffrey Stilwell, Michael Rosbash & Leslie C Griffith
Nature Neuroscience 11, 354–359
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UNC93B1 delivers nucleotide-sensing toll-like receptors to endolysosomes
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Nature 452, 234–238
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perspective
The molecular basis for public T-cell responses?
Vanessa Venturi, David A. Price, Daniel C. Douek & Miles P. Davenport
Nature Reviews Immunology 8, 231–238
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Identification of a serotonin/glutamate receptor complex implicated in psychosis
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Nature 452, 93–97
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Neuroscience: A complex in psychosis
Solomon H. Snyder
Nature 452, 38–39
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The inflammasome recognizes cytosolic microbial and host DNA and triggers an innate immune response
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Hormones of the gut–brain axis as targets for the treatment of upper gastrointestinal disorders
Gareth J. Sanger & Kevin Lee
Nature Reviews Drug Discovery 7, 241–254
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Targeting the murine serotonin transporter: insights into human neurobiology
Dennis L. Murphy & Klaus-Peter Lesch
Nature Reviews Neuroscience 9, 85–96
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Conformational cross-talk between α2A-adrenergic and μ-opioid receptors controls cell signaling
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Nature Chemical Biology 4, 126–131
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brief communication
Biosynthesis and processing of endogenous BDNF: CNS neurons store and secrete BDNF, not pro-BDNF
Tomoya Matsumoto et al.
Nature Neuroscience 11, 131–133
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The reverse stop-signal model for CTLA4 function
Christopher E. Rudd
Nature Reviews Immunology 8, 153–160
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Principles of bioactive lipid signalling: lessons from sphingolipids
Yusuf A. Hannun & Lina M. Obeid
Nature Reviews Molecular Cell Biology 9, 139–150
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Acute upregulation of an NKG2D ligand promotes rapid reorganization of a local immune compartment with pleiotropic effects on carcinogenesis
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Nature Immunology 9, 146–154
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Stress gets under your skin
Daniel M Andrews & Mark J Smyth
Nature Immunology 9, 119–120
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Anandamide inhibits metabolism and physiological actions of 2-arachidonoylglycerol in the striatum
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Nature Neuroscience 11, 152–159
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Why endocannabinoids are not all alike
Vincenzo Di Marzo & Luigia Cristino
Nature Neuroscience 11, 124–126
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Ephrin-B reverse signaling promotes structural and functional synaptic maturation in vivo
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Nature Neuroscience 11, 160–169
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perspective
How microorganisms tip the balance between interleukin-12 family members
Stanislas Goriely, Markus F. Neurath & Michel Goldman
Nature Reviews Immunology 8, 81–86
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perspective
Protein therapeutics: a summary and pharmacological classification
Benjamin Leader, Quentin J. Baca & David E. Golan
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Reversal of pathological pain through specific spinal GABAA receptor subtypes
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Heterotrimeric G protein activation by G-protein-coupled receptors
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Nature Reviews Molecular Cell Biology 9, 60–71
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Unique functions of the type II interleukin 4 receptor identified in mice lacking the interleukin 13 receptor α1 chain
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Nature Immunology 9, 25–33
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Fcγ receptors as regulators of immune responses
Falk Nimmerjahn & Jeffrey V. Ravetch
Nature Reviews Immunology 8, 34–47
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The lysophosphatidic acid receptor LPA1 links pulmonary fibrosis to lung injury by mediating fibroblast recruitment and vascular leak
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Nature Medicine 14, 45–54
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From lung injury to fibrosis
Klaus Ley & Alexander Zarbock
Nature Medicine 14, 20–21
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GEP100 links epidermal growth factor receptor signalling to Arf6 activation to induce breast cancer invasion
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Nature Cell Biology 10, 85–92
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Getting invasive with GEP100 and Arf6
Ferran Valderrama & Anne J. Ridley
Nature Cell Biology 10, 16–18
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The sphingosine 1-phosphate receptor 1 causes tissue retention by inhibiting the entry of peripheral tissue T lymphocytes into afferent lymphatics
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Nature Immunology 9, 42–53
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CD19 is essential for B cell activation by promoting B cell receptor–antigen microcluster formation in response to membrane-bound ligand
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Nature Immunology 9, 63–72
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Modification of kidney barrier function by the urokinase receptor
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Nature Medicine 14, 55–63
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An integrated model of the recognition of Candida albicans by the innate immune system
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Nature Reviews Microbiology 6, 67–78
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Semaphorin-3A guides radial migration of cortical neurons during development
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Nature Neurobiology 11, 36–44
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