Research library: Immunology
2008:
| December
| November
| October
| September
| August
| July
| June
| May
| April
| March
| February
| January
Other Years: 2002 | 2003 | 2004 | 2005 | 2006 | 2007
December
article
Nonredundant and complementary functions of TRAF2 and TRAF3 in a ubiquitination cascade that activates NIK-dependent alternative NF-κB signaling
Sivakumar Vallabhapurapu et al.
Nature Immunology 9, 1364–1370
(December 2008); doi:10.1038/ni.1678
| Summary | Full Text (HTML / PDF) |
article
Noncanonical NF-κB activation requires coordinated assembly of a regulatory complex of the adaptors cIAP1, cIAP2, TRAF2 and TRAF3 and the kinase NIK
Brian J Zarnegar et al.
Nature Immunology 9, 1371–1378
(December 2008); doi:10.1038/ni.1676
| Summary | Full Text (HTML / PDF) |
news and views
Self-termination of the terminator
David Wallach & Andrew Kovalenko
Nature Immunology 9, 1325–1327
(December 2008); doi:10.1038/ni1208-1325
| Full Text (HTML / PDF) |
article
Toll-like receptor–induced arginase 1 in macrophages thwarts effective immunity against intracellular pathogens
Karim C El Kasmi et al.
Nature Immunology 9, 1399–1406
(December 2008); doi:10.1038/ni.1671
| Summary | Full Text (HTML / PDF) |
review
Transcriptional regulation by AIRE: molecular mechanisms of central tolerance
Pärt Peterson, Tõnis Org & Ana Rebane
Nature Reviews Immunology 8, 948–957
(December 2008); doi:10.1038/nri2450
| Summary | Full Text (HTML / PDF) |
review
From bench to bedside: stealth of enteroinvasive pathogens
Renée M. Tsolis, Glenn M. Young, Jay V. Solnick & Andreas J. Bäumler
Nature Reviews Microbiology 6, 883–892
(December 2008); doi:10.1038/nrmicro2012
| Summary | Full Text (HTML / PDF) |
article
Transforming growth factor-β 'reprograms' the differentiation of T helper 2 cells and promotes an interleukin 9–producing subset
Marc Veldhoen et al.
Nature Immunology 9, 1341–1346
(December 2008); doi:10.1038/ni.1659
| Summary | Full Text (HTML / PDF) |
article
Proteolytic cleavage in an endolysosomal compartment is required for activation of Toll-like receptor 9
Boyoun Park et al.
Nature Immunology 9, 1407–1414
(December 2008); doi:10.1038/ni.1669
| Summary | Full Text (HTML / PDF) |
review
Viral evasion and subversion of pattern-recognition receptor signalling
Andrew G. Bowie & Leonie Unterholzner
Nature Reviews Immunology 8, 911–922
(December 2008); doi:10.1038/nri2436
| Summary | Full Text (HTML / PDF) |
article
Treatment of inflammatory and neuropathic pain by uncoupling Src from the NMDA receptor complex
Xue Jun Liu et al.
Nature Medicine 14, 1325–1332
(December 2008); doi:10.1038/nm.1883
| Summary | Full Text (HTML / PDF) |
news and views
Breaking the pain connection
Catherine J Pallen
Nature Medicine 14, 1313–1315
(December 2008); doi:10.1038/nm1208-1313
| Full Text (HTML / PDF) |
review
The curious case of the tumour virus: 50 years of Burkitt's lymphoma
David A. Thorley-Lawson & Martin J. Allday
Nature Reviews Microbiology 6, 913–924
(December 2008); doi:10.1038/nrmicro2015
| Summary | Full Text (HTML / PDF) |
letter
The ectodomain of Toll-like receptor 9 is cleaved to generate a functional receptor
Sarah E. Ewald et al.
Nature 456, 658–662
(04 December 2008); doi:10.1038/nature07405
| Summary | Full Text (HTML / PDF) |
article
Tonic B cell antigen receptor signals supply an NF-κB substrate for prosurvival BLyS signaling
Jason E Stadanlick et al.
Nature Immunology 9, 1379–1387
(December 2008); doi:10.1038/ni.1666
| Summary | Full Text (HTML / PDF) |
article
Neuroendocrine signals modulate the innate immunity of Caenorhabditis elegans through insulin signaling
Trupti Kawli & Man-Wah Tan
Nature Immunology 9, 1415–1424
(December 2008); doi:10.1038/ni.1672
| Summary | Full Text (HTML / PDF) |
news and views
Nervous about immunity: neuronal signals control innate immune system
Cheng-Yuan Kao, Ferdinand C O Los & Raffi V Aroian
Nature Immunology 9, 1329–1330
(December 2008); doi:10.1038/ni1208-1329
| Full Text (HTML / PDF) |
review
Nutrient sensing and inflammation in metabolic diseases
Gökhan S. Hotamisligil & Ebru Erbay
Nature Reviews Immunology 8, 923–934
(December 2008); doi:10.1038/nri2449
| Summary | Full Text (HTML / PDF) |
perspective
Immunotherapy of autoimmunity and cancer: the penalty for success
Rachel R. Caspi
Nature Reviews Immunology 8, 970–976
(December 2008); doi:10.1038/nri2438
| Summary | Full Text (HTML / PDF) |
article
CD15 expression in human myeloid cell differentiation is regulated by sialidase activity
Samah Zeineb Gadhoum & Robert Sackstein
Nature Chemical Biology 4, 751–757
(December 2008); doi:10.1038/nchembio.116
| Summary | Full Text (HTML / PDF) |
news and views
Seeing cellular sialidase transform sugars
Minoru Fukuda & Xingfeng Bao
Nature Chemical Biology 4, 721–722
(December 2008); doi:10.1038/nchembio1208-721
| Full Text (HTML / PDF) |
November
letter
Lymphoid tissue genesis induced by commensals through NOD1 regulates intestinal homeostasis
Djahida Bouskra et al.
Nature 456, 507–510
(27 November 2008); doi:10.1038/nature07450
| Summary | Full Text (HTML / PDF) |
letter
The S100A8–serum amyloid A3–TLR4 paracrine cascade establishes a pre-metastatic phase
Sachie Hiratsuka et al.
Nature Cell Biology 10, 1349–1355
(November 2008); doi:10.1038/ncb1794
| Summary | Full Text (HTML / PDF) |
article
The immunity-related GTPase Irgm1 promotes the expansion of activated CD4+ T cell populations by preventing interferon-γ-induced cell death
Carl G Feng et al.
Nature Immunology 9, 1279–1287
(November 2008); doi:10.1038/ni.1653
| Summary | Full Text (HTML / PDF) |
news and views
IFN-γ and self-absorbed CD4+ T cells: a regulatory double negative
David Hildeman & Edith Janssen
Nature Immunology 9, 1210–1212
(November 2008); doi:10.1038/ni1108-1210
| Full Text (HTML / PDF) |
review
Mammalian glycosylation in immunity
Jamey D. Marth & Prabhjit K. Grewal
Nature Reviews Immunology 8, 874–887
(November 2008); doi:10.1038/nri2417
| Summary | Full Text (HTML / PDF) |
article
5'-triphosphate-siRNA: turning gene silencing and Rig-I activation against melanoma
Hendrik Poeck et al.
Nature Medicine 14, 1256–1263
(November 2008); doi:10.1038/nm.1887
| Summary | Full Text (HTML / PDF) |
news and views
RIG-ing an antitumor response
Fabio Petrocca & Judy Lieberman
Nature Medicine 14, 1152–1153
(November 2008); doi:10.1038/nm1108-1152
| Full Text (HTML / PDF) |
article
Insights into interferon regulatory factor activation from the crystal structure of dimeric IRF5
Weijun Chen et al.
Nature Structural & Molecular Biology 15, 1213–1220
(November 2008); doi:10.1038/nsmb.1496
| Summary | Full Text (HTML / PDF) |
article
The actin regulator coronin 1A is mutant in a thymic egress–deficient mouse strain and in a patient with severe combined immunodeficiency
Lawrence R Shiow et al.
Nature Immunology 9, 1307–1315
(November 2008); doi:10.1038/ni.1662
| Summary | Full Text (HTML / PDF) |
news and views
Immunodeficiency: when T cells are stuck at home
Kristin A Hogquist
Nature Immunology 9, 1207–1208
(November 2008); doi:10.1038/ni1108-1207
| Full Text (HTML / PDF) |
review
Cross-regulation between herpesviruses and the TNF superfamily members
John R. Šedý, Patricia G. Spear & Carl F. Ware
Nature Reviews Immunology 8, 861–873
(November 2008); doi:10.1038/nri2434
| Summary | Full Text (HTML / PDF) |
article
Opposing effects of HLA class I molecules in tuning autoreactive CD8+ T cells in multiple sclerosis
Manuel A Friese et al.
Nature Medicine 14, 1227–1235
(November 2008); doi:10.1038/nm.1881
| Summary | Full Text (HTML / PDF) |
news and views
HLA class I: friend and foe of multiple sclerosis
Roland Martin
Nature Medicine 14, 1150–1151
(November 2008); doi:10.1038/nm1108-1150
| Full Text (HTML / PDF) |
perspective
Cytokines and their relationship to the symptoms and outcome of cancer
Bostjan Seruga, Haibo Zhang, Lori J. Bernstein & Ian F. Tannock
Nature Reviews Cancer 8, 887–899
(November 2008); doi:10.1038/nrc2507
| Summary | Full Text (HTML / PDF) |
review
Avoiding the void: cell-to-cell spread of human viruses
Quentin Sattentau
Nature Reviews Microbiology 6, 815–826
(November 2008); doi:10.1038/nrmicro1972
| Summary | Full Text (HTML / PDF) |
letter
A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells
Ken Cadwell et al.
Nature 456, 259–263
(13 November 2008); doi:10.1038/nature07416
| Summary | Full Text (HTML / PDF) |
letter
Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1β production
Tatsuya Saitoh et al.
Nature 456, 264–268
(13 November 2008); doi:10.1038/nature07383
| Summary | Full Text (HTML / PDF) |
article
CEACAM1 inhibits Toll-like receptor 2–triggered antibacterial responses of human pulmonary epithelial cells
Hortense Slevogt et al.
Nature Immunology 9, 1270–1278
(November 2008); doi:10.1038/ni.1661
| Summary | Full Text (HTML / PDF) |
article
Triggering the succinate receptor GPR91 on dendritic cells enhances immunity
Tina Rubic et al.
Nature Immunology 9, 1261–1269
(November 2008); doi:10.1038/ni.1657
| Summary | Full Text (HTML / PDF) |
review
TRIM family proteins and their emerging roles in innate immunity
Keiko Ozato, Dong-Mi Shin, Tsung-Hsien Chang & Herbert C. Morse III
Nature Reviews Immunology 8, 849–860
(November 2008); doi:10.1038/nri2413
| Summary | Full Text (HTML / PDF) |
article
Modulation of the antitumor immune response by complement
Maciej M Markiewski et al.
Nature Immunology 9, 1225–1235
(November 2008); doi:10.1038/ni.1655
| Summary | Full Text (HTML / PDF) |
news and views
Cancer exploiting complement: a clue or an exception?
Bruce E Loveland & Jonathan Cebon
Nature Immunology 9, 1205–1206
(November 2008); doi:10.1038/ni1108-1205
| Full Text (HTML / PDF) |
article
Priming for T helper type 2 differentiation by interleukin 2—mediated induction of interleukin 4 receptor α-chain expression
Wei Liao et al.
Nature Immunology 9, 1288–1296
(November 2008); doi:10.1038/ni.1656
| Summary | Full Text (HTML / PDF) |
article
Interactions among the transcription factors Runx1, RORγt and Foxp3 regulate the differentiation of interleukin 17–producing T cells
Fuping Zhang, Guangxun Meng & Warren Strober
Nature Immunology 9, 1297–1306
(November 2008); doi:10.1038/ni.1663
| Summary | Full Text (HTML / PDF) |
review
New regulators of NF-κB in inflammation
Sankar Ghosh & Matthew S. Hayden
Nature Reviews Immunology 8, 837–848
(November 2008); doi:10.1038/nri2423
| Summary | Full Text (HTML / PDF) |
October
article
Sensing of 'danger signals' and pathogen-associated molecular patterns defines binary signaling pathways 'upstream' of Toll
Laure El Chamy, Vincent Leclerc, Isabelle Caldelari & Jean-Marc Reichhart
Nature Immunology 9, 1165–1170
(October 2008); doi:10.1038/ni.1643
| Summary | Full Text (HTML / PDF) |
review
The alliance of sphingosine-1-phosphate and its receptors in immunity
Juan Rivera, Richard L. Proia & Ana Olivera
Nature Reviews Immunology 8, 753–763
(October 2008); doi:10.1038/nri2400
| Summary | Full Text (HTML / PDF) |
review
The IL-33/ST2 pathway: therapeutic target and novel biomarker
Rahul Kakkar & Richard T. Lee
Nature Reviews Drug Discovery 7, 827–840
(October 2008); doi:10.1038/nrd2660
| Summary | Full Text (HTML / PDF) |
letter
Innate immunity and intestinal microbiota in the development of Type 1 diabetes
Li Wen et al.
Nature 455, 1109–1113
(23 October 2008); doi:10.1038/nature07336
| Summary | Full Text (HTML / PDF) |
article
Mincle is an ITAM-coupled activating receptor that senses damaged cells
Sho Yamasaki, Eri Ishikawa, Machie Sakuma, Hiromitsu Hara, Koji Ogata & Takashi Saito
Nature Immunology 9, 1179–1188
(October 2008); doi:10.1038/ni.1651
| Summary | Full Text (HTML / PDF) |
news and views
Sensing necrosis with Mincle
Gordon D Brown
Nature Immunology 9, 1099–1100
(October 2008); doi:10.1038/ni1008-1099
| Full Text (HTML / PDF) |
article
Divergent TLR7 and TLR9 signaling and type I interferon production distinguish pathogenic and nonpathogenic AIDS virus infections
Judith N. Mandl et al.
Nature Medicine 14, 1077–1087
(October 2008); doi:10.1038/nm.1871
| Summary | Full Text (HTML / PDF) |
news and views
Immune alteration fends off AIDS
Karen O'Connell & Robert F Siliciano
Nature Medicine 14, 1016–1018
(October 2008); doi:10.1038/nm1008-1016
| Full Text (HTML / PDF) |
article
Notch2 integrates signaling by the transcription factors RBP-J and CREB1 to promote T cell cytotoxicity
Yoichi Maekawa et al.
Nature Immunology 9, 1140–1147
(October 2008); doi:10.1038/ni.1649
| Summary | Full Text (HTML / PDF) |
article
Toll-like receptor—mediated induction of type I interferon in plasmacytoid dendritic cells requires the rapamycin-sensitive PI(3)K-mTOR-p70S6K pathway
Weiping Cao et al.
Nature Immunology 9, 1157–1164
(October 2008); doi:10.1038/ni.1645
| Summary | Full Text (HTML / PDF) |
news and views
RAPping production of type I interferon in pDCs through mTOR
Mauro Costa-Mattioli & Nahum Sonenberg
Nature Immunology 9, 1097–1099
(October 2008); doi:10.1038/ni1008-1097
| Full Text (HTML / PDF) |
review
Harmful molecular mechanisms in sepsis
Daniel Rittirsch, Michael A. Flierl & Peter A. Ward
Nature Reviews Immunology 8, 776–787
(October 2008); doi:10.1038/nri2402
| Summary | Full Text (HTML / PDF) |
article
SAP-controlled T–B cell interactions underlie germinal centre formation
Hai Qi, Jennifer L. Cannons, Frederick Klauschen, Pamela L. Schwartzberg & Ronald N. Germain
Nature 455, 764–769
(9 October 2008); doi:10.1038/nature07345
| Summary | Full Text (HTML / PDF) |
news and views
Immunology: Helpful T cells are sticky
Elissa K. Deenick & Stuart G. Tangye
Nature 455, 745–747
(9 October 2008); doi:10.1038/455745a
| Full Text (HTML / PDF) |
perspective
A signal-switch hypothesis for cross-regulation of cytokine and TLR signalling pathways
Lionel B. Ivashkiv
Nature Reviews Immunology 8, 816–822
(October 2008); doi:10.1038/nri2396
| Summary | Full Text (HTML / PDF) |
letter
STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling
Hiroki Ishikawa & Glen N. Barber
Nature 455, 674–678
(2 October 2008); doi:10.1038/nature07317
| Summary | Full Text (HTML / PDF) |
article
Cascading suppression of transcriptional silencers by ThPOK seals helper T cell fate
Sawako Muroi et al.
Nature Immunology 9, 1113–1121
(October 2008); doi:10.1038/ni.1650
| Summary | Full Text (HTML / PDF) |
article
Distinct functions for the transcription factors GATA-3 and ThPOK during intrathymic differentiation of CD4+ T cells
Lie Wang et al.
Nature Immunology 9, 1122–1130
(October 2008); doi:10.1038/ni.1647
| Summary | Full Text (HTML / PDF) |
article
ThPOK acts late in specification of the helper T cell lineage and suppresses Runx-mediated commitment to the cytotoxic T cell lineage
Takeshi Egawa & Dan R Littman
Nature Immunology 9, 1131–1139
(October 2008); doi:10.1038/ni.1652
| Summary | Full Text (HTML / PDF) |
news and views
Putting ThPOK in place
J Jeremiah Bell & Avinash Bhandoola
Nature Immunology 9, 1095–1096
(October 2008); doi:10.1038/ni1008-1095;
| Full Text (HTML / PDF) |
September
letter
FcRn-mediated antibody transport across epithelial cells revealed by electron tomography
Wanzhong He et al.
Nature 455, 542–546
(25 September 2008); doi:10.1038/nature07255
| Summary | Full Text (HTML / PDF) |
article
The kinase p38α serves cell type—specific inflammatory functions in skin injury and coordinates pro- and anti-inflammatory gene expression
Chun Kim et al.
Nature Immunology 9, 1019–1027
(September 2008); doi:10.1038/ni.1640
| Summary | Full Text (HTML / PDF) |
review
Orchestrating the orchestrators: chemokines in control of T cell traffic
Shannon K Bromley, Thorsten R Mempel & Andrew D Luster
Nature Immunology 9, 970–980
(September 2008); doi:10.1038/ni.f.213
| Summary | Full Text (HTML / PDF) |
review
Tailoring T-cell receptor signals by proximal negative feedback mechanisms
Oreste Acuto, Vincenzo Di Bartolo & Frédérique Michel
Nature Reviews Immunology 8, 699–712
(September 2008); doi:10.1038/nri2397
| Summary | Full Text (HTML / PDF) |
letter
Platelet-derived growth factor-α receptor activation is required for human cytomegalovirus infection
Liliana Soroceanu, Armin Akhavan & Charles S. Cobbs
Nature 455, 391–395
(18 September 2008); doi:10.1038/nature07209
| Summary | Full Text (HTML / PDF) |
article
Human microRNAs regulate stress-induced immune responses mediated by the receptor NKG2D
Noam Stern-Ginossar et al.
Nature Immunology 9, 1065–1073
(September 2008); doi:10.1038/ni.1642
| Summary | Full Text (HTML / PDF) |
news and views
Regulation of NKG2D ligands: a purposeful but delicate affair
Thomas Spies
Nature Immunology 9, 1013–1015
(September 2008); doi:10.1038/ni0908-1013
| Full Text (HTML / PDF) |
review
Adenosine receptors: therapeutic aspects for inflammatory and immune diseases
György Haskó, Joel Linden, Bruce Cronstein & Pál Pacher
Nature Reviews Drug Discovery 7, 759–770
(September 2008); doi:10.1038/nrd2638
| Summary | Full Text (HTML / PDF) |
letter
T-cell-expressed proprotein convertase furin is essential for maintenance of peripheral immune tolerance
Marko Pesu et al.
Nature 455, 246–250
(11 September 2008); doi:10.1038/nature07210
| Summary | Full Text (HTML / PDF) |
article
Function of TRADD in tumor necrosis factor receptor 1 signaling and in TRIF-dependent inflammatory responses
Maria A Ermolaeva et al.
Nature Immunology 9, 1037–1046
(September 2008); doi:10.1038/ni.1638
| Summary | Full Text (HTML / PDF) |
article
The function of TRADD in signaling through tumor necrosis factor receptor 1 and TRIF-dependent Toll-like receptors
Yelena L Pobezinskaya et al.
Nature Immunology 9, 1047–1054
(September 2008); doi:10.1038/ni.1639
| Summary | Full Text (HTML / PDF) |
news and views
A birthday gift for TRADD
Gioacchino Natoli & Liv M I Austenaa
Nature Immunology 9, 1015–1016
(September 2008); doi:10.1038/ni0908-1015
| Full Text (HTML / PDF) |
review
The endoplasmic reticulum stress response in immunity and autoimmunity
Derrick J. Todd, Ann-Hwee Lee & Laurie H. Glimcher
Nature Reviews Immunology 8, 663–674
(September 2008); doi:10.1038/nri2359
| Summary | Full Text (HTML / PDF) |
article
The kinases MSK1 and MSK2 act as negative regulators of Toll-like receptor signaling
Olga Ananieva et al.
Nature Immunology 9, 1028–1036
(September 2008); doi:10.1038/ni.1644
| Summary | Full Text (HTML / PDF) |
article
A critical function for CD200 in lung immune homeostasis and the severity of influenza infection
Robert J Snelgrove et al.
Nature Immunology 9, 1074–1083
(September 2008); doi:10.1038/ni.1637
| Summary | Full Text (HTML / PDF) |
news and views
The CD200-CD200R axis in local control of lung inflammation
Patrick G Holt & Deborah H Strickland
Nature Immunology 9, 1011–1013
(September 2008); doi:10.1038/ni0908-1011
| Full Text (HTML / PDF) |
review
Vitamin effects on the immune system: vitamins A and D take centre stage
J. Rodrigo Mora, Makoto Iwata & Ulrich H. von Andrian
Nature Reviews Immunology 8, 685–698
(September 2008); doi:10.1038/nri2378
| Summary | Full Text (HTML / PDF) |
August
article
Actin restricts FcεRI diffusion and facilitates antigen-induced receptor immobilization
Nicholas L. Andrews et al.
Nature Cell Biology 10, 955–963
(August 2008); doi:10.1038/ncb1755
| Summary | Full Text (HTML / PDF) |
review
Cancer as an overhealing wound: an old hypothesis revisited
Matthias Schäfer & Sabine Werner
Nature Reviews Molecular Cell Biology 9, 628–638
(August 2008); doi:10.1038/nrm2455
| Summary | Full Text (HTML / PDF) |
article
Superoxide dismutase 1 regulates caspase-1 and endotoxic shock
Felix Meissner, Kaaweh Molawi & Arturo Zychlinsky
Nature Immunology 9, 866–872
(August 2008); doi:10.1038/ni.1633
| Summary | Full Text (HTML / PDF) |
article
Differently phosphorylated forms of the cortactin homolog HS1 mediate distinct functions in natural killer cells
Boyd Butler, Diana H Kastendieck & John A Cooper
Nature Immunology 9, 887–897
(August 2008); doi:10.1038/ni.1630
| Summary | Full Text (HTML / PDF) |
news and views
Distinct functions for HS1 in chemosensory versus adhesive signaling
Peter Beemiller & Matthew F Krummel
Nature Immunology 9, 833–834
(August 2008); doi:10.1038/ni0808-833
| Full Text (HTML / PDF) |
review
The known unknowns of antigen processing and presentation
Jatin M. Vyas, Annemarthe G. Van der Veen & Hidde L. Ploegh
Nature Reviews Immunology 8, 607–618
(August 2008); doi:10.1038/nri2368
| Summary | Full Text (HTML / PDF) |
perspective
Neutralizing antibodies to therapeutic enzymes: considerations for testing, prevention and treatment
Jinhai Wang et al.
Nature Biotechnology 26, 901–908
(August 2008); doi:10.1038/nbt.1484
| Summary | Full Text (HTML / PDF) |
article
Nonmuscle myosin light-chain kinase mediates neutrophil transmigration in sepsis-induced lung inflammation by activating β2 integrins
Jingsong Xu et al.
Nature Immunology 9, 880–886
(August 2008); doi:10.1038/ni.1628
| Summary | Full Text (HTML / PDF) |
review
WNT signalling in the immune system: WNT is spreading its wings
Frank J. T. Staal, Tiago C. Luis & Machteld M. Tiemessen
Nature Reviews Immunology 8, 581–593
(August 2008); doi:10.1038/nri2360
| Summary | Full Text (HTML / PDF) |
article
The DEAD-box helicase DDX3X is a critical component of the TANK-binding kinase 1-dependent innate immune response
Didier Soulat et al.
The EMBO Journal 27, 2135–2146
(August 2008); doi:10.1038/emboj.2008.126
| Summary | Full Text (HTML / PDF) |
article
Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization
Veit Hornung et al.
Nature Immunology 9, 847–856
(August 2008); doi:10.1038/ni.1631
| Summary | Full Text (HTML / PDF) |
article
The NALP3 inflammasome is involved in the innate immune response to amyloid-β
Annett Halle et al.
Nature Immunology 9, 857–865
(August 2008); doi:10.1038/ni.1636
| Summary | Full Text (HTML / PDF) |
news and views
NLRs and the dangers of pollution and aging
Stephen B Willingham & Jenny P-Y Ting
Nature Immunology 9, 831–833
(August 2008); doi:10.1038/ni0808-831
| Full Text (HTML / PDF) |
review
Plasmacytoid dendritic cells: sensing nucleic acids in viral infection and autoimmune diseases
Michel Gilliet, Wei Cao & Yong-Jun Liu
Nature Reviews Immunology 8, 594–606
(August 2008); doi:10.1038/nri2358
| Summary | Full Text (HTML / PDF) |
article
An essential function for β-arrestin 2 in the inhibitory signaling of natural killer cells
Ming-Can Yu et al.
Nature Immunology 9, 898–907
(August 2008); doi:10.1038/ni.1635
| Summary | Full Text (HTML / PDF) |
news and views
Arrestin NK cell cytotoxicity
Yenan T Bryceson & Hans-Gustaf Ljunggren
Nature Immunology 9, 835–836
(August 2008); doi:10.1038/ni0808-835
| Full Text (HTML / PDF) |
progress
New roles for TIM family members in immune regulation
Vijay K. Kuchroo, Valerie Dardalhon, Sheng Xiao & Ana C. Anderson
Nature Reviews Immunology 8, 577–580
(August 2008); doi:10.1038/nri2366
| Summary | Full Text (HTML / PDF) |
July
review
Origin and physiological roles of inflammation
Ruslan Medzhitov
Nature 454, 428–435
(24 July 2008); doi:10.1038/nature07201
| Summary | Full Text (HTML / PDF) |
review
Cancer-related inflammation
Alberto Mantovani, Paola Allavena, Antonio Sica & Frances Balkwill
Nature 454, 436–444
(24 July 2008); doi:10.1038/nature07205
| Summary | Full Text (HTML / PDF) |
review
The development of allergic inflammation
Stephen J. Galli, Mindy Tsai & Adrian M. Piliponsky
Nature 454, 445–454
(24 July 2008); doi:10.1038/nature07204
| Summary | Full Text (HTML / PDF) |
review
From endoplasmic-reticulum stress to the inflammatory response
Kezhong Zhang & Randal J. Kaufman
Nature 454, 455–462
(24 July 2008); doi:10.1038/nature07203
| Summary | Full Text (HTML / PDF) |
review
Integration of metabolism and inflammation by lipid-activated nuclear receptors
Steven J. Bensinger & Peter Tontonoz
Nature 454, 470–477
(24 July 2008); doi:10.1038/nature07202
| Summary | Full Text (HTML / PDF) |
article
Structure of and influence of a tick complement inhibitor on human complement component 5
Folmer Fredslund et al.
Nature Immunology 9, 753–760
(July 2008); doi:10.1038/ni.1625
| Summary | Full Text (HTML / PDF) |
article
Regulation of humoral and cellular gut immunity by lamina propria dendritic cells expressing Toll-like receptor 5
Satoshi Uematsu et al.
Nature Immunology 9, 769–776
(July 2008); doi:10.1038/ni.1622
| Summary | Full Text (HTML / PDF) |
article
TRPM2-mediated Ca2+ influx induces chemokine production in monocytes that aggravates inflammatory neutrophil infiltration
Shinichiro Yamamoto et al.
Nature Medicine 14, 738–747
(July 2008); doi:10.1038/nm1758
| Summary | Full Text (HTML / PDF) |
brief communication
A second binding site for double-stranded RNA in TLR3 and consequences for interferon activation
Nina Pirher, Karolina Ivičak, Jelka Pohar, Mojca Benčina & Roman Jerala
Nature Structural & Molecular Biology 15, 761–763
(July 2008); doi:10.1038/nsmb.1453
| Summary | Full Text (HTML / PDF) |
letter
IL-21 and TGF-β are required for differentiation of human TH17 cells
Li Yang et al.
Nature 454, 350–352
(17 July 2008); doi:10.1038/nature07021
| Summary | Full Text (HTML / PDF) |
article
PTEN functions to 'prioritize' chemotactic cues and prevent 'distraction' in migrating neutrophils
Bryan Heit et al.
Nature Immunology 9, 743–752
(July 2008); doi:10.1038/ni.1623
| Summary | Full Text (HTML / PDF) |
news and views
PTEN gives neutrophils direction
Daniel D Billadeau
Nature Immunology 9, 716–718
(July 2008); doi:10.1038/ni0708-716
| Full Text (HTML / PDF) |
review
How regulatory T cells work
Dario A. A. Vignali, Lauren W. Collison & Creg J. Workman
Nature Reviews Immunology 8, 523–532
(July 2008); doi:10.1038/nri2343
| Summary | Full Text (HTML / PDF) |
research
Treatment of arthritis with a selective inhibitor of c-Fos/activator protein-1
Yukihiko Aikawa et al.
Nature Biotechnology 26, 817–823
(July 2008); doi:10.1038/nbt1412
| Summary | Full Text (HTML / PDF) |
article
An autonomous CDR3δ is sufficient for recognition of the nonclassical MHC class I molecules T10 and T22 by γδ T cells
Erin J Adams, Pavel Strop, Sunny Shin, Yueh-Hsiu Chien & K Christopher Garcia
Nature Immunology 9, 777–784
(July 2008); doi:10.1038/ni.1620
| Summary | Full Text (HTML / PDF) |
review
Deubiquitylation and regulation of the immune response
Shao-Cong Sun
Nature Reviews Immunology 8, 501–511
(July 2008); doi:10.1038/nri2337
| Summary | Full Text (HTML / PDF) |
article
A Toll-like receptor 2–integrin β3 complex senses bacterial lipopeptides via vitronectin
Gisa Gerold et al.
Nature Immunology 9, 761–768
(July 2008); doi:10.1038/ni.1618
| Summary | Full Text (HTML / PDF) |
article
The transcription factor Erg is essential for definitive hematopoiesis and the function of adult hematopoietic stem cells
Stephen J Loughran et al.
Nature Immunology 9, 810–819
(July 2008); doi:10.1038/ni.1617
| Summary | Full Text (HTML / PDF) |
news and views
Erg in stem cells: a function emerges
Ellen V Rothenberg
Nature Immunology 9, 714–716
(July 2008); doi:10.1038/ni0708-714
| Full Text (HTML / PDF) |
review
Colony-stimulating factors in inflammation and autoimmunity
John A. Hamilton
Nature Reviews Immunology 8, 533–544
(July 2008); doi:10.1038/nri2356
| Summary | Full Text (HTML / PDF) |
June
article
A critical function for TGF-β signaling in the development of natural CD4+CD25+Foxp3+ regulatory T cells
Yongzhong Liu et al.
Nature Immunology 9, 632–640
(June 2008); doi:10.1038/ni.1607
| Summary | Full Text (HTML / PDF) |
article
The differentiation of human TH-17 cells requires transforming growth factor-β and induction of the nuclear receptor RORγt
Nicolas Manel, Derya Unutmaz & Dan R Littman
Nature Immunology 9, 641–649
(June 2008); doi:10.1038/ni.1610
| Summary | Full Text (HTML / PDF) |
article
A critical function for transforming growth factor-β, interleukin 23 and proinflammatory cytokines in driving and modulating human TH-17 responses
Elisabetta Volpe et al.
Nature Immunology 9, 650–657
(June 2008); doi:10.1038/ni.1613
| Summary | Full Text (HTML / PDF) |
news and views
Differentiation of human TH-17 cells does require TGF-β!
Anne O'Garra, Brigitta Stockinger & Marc Veldhoen
Nature Immunology 9, 588–590
(June 2008); doi:10.1038/ni0608-588
| Full Text (HTML / PDF) |
article
Persistent activation of an innate immune response translates respiratory viral infection into chronic lung disease
Edy Y Kim et al.
Nature Medicine 14, 633–640
(June 2008); doi:10.1038/nm1770
| Summary | Full Text (HTML / PDF) |
news and views
Lung NKT cell commotion takes your breath away
Sebastian Joyce & Luc Van Kaer
Nature Medicine 14, 609–610
(June 2008); doi:10.1038/nm0608-609
| Full Text (HTML / PDF) |
article
Scalable signaling mediated by T cell antigen receptor-CD3 ITAMs ensures effective negative selection and prevents autoimmunity
Jeff Holst et al.
Nature Immunology 9, 658–666
(June 2008); doi:10.1038/ni.1611
| Summary | Full Text (HTML / PDF) |
news and views
CD3 ITAMs count!
Bernard Malissen
Nature Immunology 9, 583–584
(June 2008); doi:10.1038/ni0608-583
| Full Text (HTML / PDF) |
article
The receptor tyrosine kinase Flt3 is required for dendritic cell development in peripheral lymphoid tissues
Claudia Waskow et al.
Nature Immunology 9, 676–683
(June 2008); doi:10.1038/ni.1615
| Summary | Full Text (HTML / PDF) |
news and views
Homeostasis of dendritic cell pool in lymphoid organs
Cedric Auffray, Yalin Emre & Frederic Geissmann
Nature Immunology 9, 584–586
(June 2008); doi:10.1038/ni0608-584
| Full Text (HTML / PDF) |
letter
Blocking TGF-β-Smad2/3 innate immune signaling mitigates Alzheimer-like pathology
Terrence Town et al.
Nature Medicine 14, 681–687
(June 2008); doi:10.1038/nm1781
| Summary | Full Text (HTML / PDF) |
letter
Draper-dependent glial phagocytic activity is mediated by Src and Syk family kinase signalling
Jennifer S. Ziegenfuss et al.
Nature 453, 935–939
(12 June 2008); doi:10.1038/nature06901
| Summary | Full Text (HTML / PDF) |
article
Foxo1 directly regulates the transcription of recombination-activating genes during B cell development
Rupesh H Amin & Mark S Schlissel
Nature Immunology 9, 613–622
(June 2008); doi:10.1038/ni.1612
| Summary | Full Text (HTML / PDF) |
article
SLP-65 regulates immunoglobulin light chain gene recombination through the PI(3)K–PKB–Foxo pathway
Sebastian Herzog et al.
Nature Immunology 9, 623–631
(June 2008); doi:10.1038/ni.1616
| Summary | Full Text (HTML / PDF) |
news and views
Foxos around make B cells tolerable
Marta A W Rowh & Craig H Bassing
Nature Immunology 9, 586–588
(June 2008); doi:10.1038/ni0608-586
| Full Text (HTML / PDF) |
article
Transcription factor Mef2c is required for B cell proliferation and survival after antigen receptor stimulation
Peter R Wilker et al.
Nature Immunology 9, 603–612
(June 2008); doi:10.1038/ni.1609
| Summary | Full Text (HTML / PDF) |
review
Inhibitory B7-family molecules in the tumour microenvironment
Weiping Zou & Lieping Chen
Nature Reviews Immunology 8, 467–477
(June 2008); doi:10.1038/nri2326
| Summary | Full Text (HTML / PDF) |
article
SUMOylation of Krüppel-like transcription factor 5 acts as a molecular switch in transcriptional programs of lipid metabolism involving PPAR-δ
Yumiko Oishi et al.
Nature Medicine 14, 656–666
(June 2008); doi:10.1038/nm1756
| Summary | Full Text (HTML / PDF) |
news and views
Multiple layers of metabolism
Mukesh K Jain
Nature Medicine 14, 603–604
(June 2008); doi:10.1038/nm0608-603
| Summary | Full Text (HTML / PDF) |
letter
NF-κB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1α
Jordi Rius et al.
Nature 453, 807–811
(5 June 2008); doi:10.1038/nature06905
| Summary | Full Text (HTML / PDF) |
article
Sequential control of Toll-like receptor–dependent responses by IRAK1 and IRAK2
Tatsukata Kawagoe et al.
Nature Immunology 9, 684–691
(June 2008); doi:10.1038/ni.1606
| Summary | Full Text (HTML / PDF) |
news and views
IRAK2 takes its place in TLR signaling
Etienne Meylan & Jürg Tschopp
Nature Immunology 9, 581–582
(June 2008); doi:10.1038/ni0608-581
| Full Text (HTML / PDF) |
review
Inhibitory B7-family molecules in the tumour microenvironment
Weiping Zou & Lieping Chen
Nature Reviews Immunology 8, 467–477
(June 2008); doi:10.1038/nri2326
| Summary | Full Text (HTML / PDF) |
May
article
A microbial symbiosis factor prevents intestinal inflammatory disease
Sarkis K. Mazmanian, June L. Round & Dennis L. Kasper
Nature 453, 620–625
(29 May 2008); doi:10.1038/nature07008
| Summary | Full Text (HTML / PDF) |
letter
CLEC5A is critical for dengue-virus-induced lethal disease
Szu-Ting Chen et al.
Nature 453, 672–676
(29 May 2008); doi:10.1038/nature07013
| Summary | Full Text (HTML / PDF) |
article
The proline-rich sequence of CD3ε controls T cell antigen receptor expression on and signaling potency in preselection CD4+CD8+ thymocytes
Michaël Mingueneau et al.
Nature Immunology 9, 522–532
(May 2008); doi:10.1038/ni.1608
| Summary | Full Text (HTML / PDF) |
news and views
CD3ε: PeRuSing for positive selection
Jonathan S Maltzman & Gary A Koretzky
Nature Immunology 9, 457–459
(May 2008); doi:10.1038/ni0508-457
| Full Text (HTML / PDF) |
review
Molecular pathogenesis of T-cell leukaemia and lymphoma
Iannis Aifantis, Elizabeth Raetz & Silvia Buonamici
Nature Reviews Immunology 8, 380–390
(May 2008); doi:10.1038/nri2304
| Summary | Full Text (HTML / PDF) |
article
Phosphatase SHP-1 promotes TLR- and RIG-I-activated production of type I interferon by inhibiting the kinase IRAK1
Huazhang An et al.
Nature Immunology 9, 542–550
(May 2008); doi:10.1038/ni.1604
| Summary | Full Text (HTML / PDF) |
news and views
'Fine tuning' TLR signaling
Luke A J O'Neill
Nature Immunology 9, 459–461
(May 2008); doi:10.1038/ni0508-459
| Full Text (HTML / PDF) |
review
Immunobiology of the TAM receptors
Greg Lemke & Carla V. Rothline
Nature Reviews Immunology 8, 327–336
(May 2008); doi:10.1038/nri2303
| Summary | Full Text (HTML / PDF) |
review
TH17 cells in development: an updated view of their molecular identity and genetic programming
Chen Dong
Nature Reviews Immunology 8, 337–348
(May 2008); doi:10.1038/nri2295
| Summary | Full Text (HTML / PDF) |
article
Activation of c-Kit in dendritic cells regulates T helper cell differentiation and allergic asthma
Nandini Krishnamoorthy et al.
Nature Medicine 14, 565–573
(May 2008); doi:10.1038/nm1766
| Summary | Full Text (HTML / PDF) |
news and views
Dust mites' dirty dealings with dendritic cells
Dean Sheppard
Nature Medicine 14, 487–488
(May 2008); doi:10.1038/nm0508-487
| Summary | Full Text (HTML / PDF) |
article
Deactivation of the kinase IKK by CUEDC2 through recruitment of the phosphatase PP1
Hui-Yan Li et al.
Nature Immunology 9, 533–541
(May 2008); doi:10.1038/ni.1600
| Summary | Full Text (HTML / PDF) |
review
Up on the tightrope: natural killer cell activation and inhibition
Lewis L Lanier
Nature Immunology 9, 495–502
(May 2008); doi:10.1038/ni1581
| Summary | Full Text (HTML / PDF) |
review
Resolving inflammation: dual anti-inflammatory and pro-resolution lipid mediators
Charles N. Serhan, Nan Chiang & Thomas E. Van Dyke
Nature Reviews Immunology 8, 349–361
(May 2008); doi:10.1038/nri2294
| Summary | Full Text (HTML / PDF) |
article
Functional roles for C5a receptors in sepsis
Daniel Rittirsch et al.
Nature Medicine 14, 551–557
(May 2008); doi:10.1038/nm1753
| Summary | Full Text (HTML / PDF) |
letter
TGF-β-induced Foxp3 inhibits TH17 cell differentiation by antagonizing ROR γt function
Liang Zhou et al.
Nature 453, 236–240
(8 May 2008); doi:10.1038/nature06878
| Summary | Full Text (HTML / PDF) |
article
Phosphatidylinositol-3-OH kinase and nutrient-sensing mTOR pathways control T lymphocyte trafficking
Linda V Sinclair et al.
Nature Immunology 9, 513–521
(May 2008); doi:10.1038/ni.1603
| Summary | Full Text (HTML / PDF) |
news and views
Moving out: mobilizing activated T cells from lymphoid tissues
Gabriel Berstein & Robert T Abraham
Nature Immunology 9, 455–457
(May 2008); doi:10.1038/ni0508-455
| Full Text (HTML / PDF) |
review
NLRs at the intersection of cell death and immunity
Jenny P.-Y. Ting, Stephen B. Willingham & Daniel T. Bergstralh
Nature Reviews Immunology 8, 372–379
(May 2008); doi:10.1038/nri2296
| Summary | Full Text (HTML / PDF) |
perspective
Not always the bad guys: B cells as regulators of autoimmune pathology
Simon Fillatreau, David Gray & Stephen M. Anderton
Nature Reviews Immunology 8, 391–397
(May 2008); doi:10.1038/nri2315
| Summary | Full Text (HTML / PDF) |
article
CD3-specific antibody-induced immune tolerance involves transforming growth factor-β from phagocytes digesting apoptotic T cells
Sylvain Perruche, Pin Zhang, Yongzhong Liu, Philippe Saas, Jeffrey A Bluestone & WanJun Chen
Nature Medicine 14, 528–535
(May 2008); doi:10.1038/nm1749
| Summary | Full Text (HTML / PDF) |
article
Rapid leukocyte migration by integrin-independent flowing and squeezing
Tim Lämmermann et al.
Nature 453, 51–55
(1 May 2008); doi:10.1038/nature06887
| Summary | Full Text (HTML / PDF) |
article
Control of Treg and TH17 cell differentiation by the aryl hydrocarbon receptor
Francisco J. Quintana et al.
Nature 453, 65–71
(1 May 2008); doi:10.1038/nature06880
| Summary | Full Text (HTML / PDF) |
letter
The aryl hydrocarbon receptor links TH17-cell-mediated autoimmunity to environmental toxins
Marc Veldhoen et al.
Nature 453, 106–109
(1 May 2008); doi:10.1038/nature06881
| Summary | Full Text (HTML / PDF) |
news and views
Immunology: T cells hang in the balance
Emily A. Stevens & Christopher A. Bradfield
Nature 453, 46–47
(1 May 2008); doi:10.1038/453046a
| Full Text (HTML / PDF) |
article
Direct proteasome-independent cross-presentation of viral antigen by plasmacytoid dendritic cells on major histocompatibility complex class I
Tiziana Di Pucchio et al.
Nature Immunology 9, 551–557
(May 2008); doi:10.1038/ni.1602
| Summary | Full Text (HTML / PDF) |
article
Spatial and mechanistic separation of cross-presentation and endogenous antigen presentation
Sven Burgdorf, Christian Schölz, Andreas Kautz, Robert Tampé & Christian Kurts
Nature Immunology 9, 558–566
(May 2008); doi:10.1038/ni.1601
| Summary | Full Text (HTML / PDF) |
news and views
Cross-presentation: avoiding trafficking chaos?
Sudhir Pai Kasturi & Bali Pulendran
Nature Immunology 9, 461–463
(May 2008); doi:10.1038/ni0508-461
| Full Text (HTML / PDF) |
review
CCR7 and its ligands: balancing immunity and tolerance
Reinhold Förster, Ana Clara Davalos-Misslitz & Antal Rot
Nature Reviews Immunology 8, 362–371
(May 2008); doi:10.1038/nri2297
| Summary | Full Text (HTML / PDF) |
letter
Jund is a determinant of macrophage activation and is associated with glomerulonephritis susceptibility
Jacques Behmoaras et al.
Nature Genetics 40, 553–559
(May 2008); doi:10.1038/ng.137
| Summary | Full Text (HTML / PDF) |
review
The TWEAK–Fn14 cytokine–receptor axis: discovery, biology and therapeutic targeting
Jeffrey A. Winkles
Nature Reviews Drug Discovery 7, 411–425
(May 2008); doi:10.1038/nrd2488
| Summary | Full Text (HTML / PDF) |
April
article
TRIM30α negatively regulates TLR-mediated NF-κB activation by targeting TAB2 and TAB3 for degradation
Mude Shi et al.
Nature Immunology 9, 369–377
(April 2008); doi:10.1038/ni1577
| Summary | Full Text (HTML / PDF) |
news and views
TRIM-ing down Tolls
Andrew G Bowie
Nature Immunology 9, 348–350
(April 2008); doi:10.1038/ni0408-348
| Full Text (HTML / PDF) |
article
Subversion of Toll-like receptor signaling by a unique family of bacterial Toll/interleukin-1 receptor domain-containing proteins
Christine Cirl et al.
Nature Medicine 14, 399–406
(April 2008); doi:10.1038/nm1734
| Summary | Full Text (HTML / PDF) |
news and views
Bacteria fight back against Toll-like receptors
Luke A J O'Neill
Nature Medicine 14, 370–372
(April 2008); doi:10.1038/nm0408-370
| Summary | Full Text (HTML / PDF) |
article
TNF activates an IRF1-dependent autocrine loop leading to sustained expression of chemokines and STAT1-dependent type I interferon–response genes
Anna Yarilina et al.
Nature Immunology 9, 378–387
(April 2008); doi:10.1038/ni1576
| Summary | Full Text (HTML / PDF) |
article
Autotaxin, an ectoenzyme that produces lysophosphatidic acid, promotes the entry of lymphocytes into secondary lymphoid organs
Hidenobu Kanda, Rebecca Newton, Russell Klein, Yuka Morita, Michael D Gunn & Steven D Rosen
Nature Immunology 9, 415–423
(April 2008); doi:10.1038/ni1573
| Summary | Full Text (HTML / PDF) |
news and views
A new player in lymphocyte homing
Dietmar Vestweber & Martin K Wild
Nature Immunology 9, 347–348
(April 2008); doi:10.1038/ni0408-347
| Full Text (HTML / PDF) |
review
Cis interactions of immunoreceptors with MHC and non-MHC ligands
Werner Held & Roy A. Mariuzza
Nature Reviews Immunology 8, 269–278
(April 2008); doi:10.1038/nri2278
| Summary | Full Text (HTML / PDF) |
letter
Impaired TH17 cell differentiation in subjects with autosomal dominant hyper-IgE syndrome
Joshua D. Milner et al.
Nature 452, 773–776
(10 April 2008); doi:10.1038/nature06764
| Summary | Full Text (HTML / PDF) |
article
TRAM couples endocytosis of Toll-like receptor 4 to the induction of interferon-β
Jonathan C Kagan, Tian Su, Tiffany Horng, Amy Chow, Shizuo Akira & Ruslan Medzhitov
Nature Immunology 9, 361–368
(April 2008); doi:10.1038/ni1569
| Summary | Full Text (HTML / PDF) |
news and views
Location, location, location: identifying the neighborhoods of LPS signaling
Colin Watts
Nature Immunology 9, 343–345
(April 2008); doi:10.1038/ni0408-343
| Full Text (HTML / PDF) |
article
Sequence- and target-independent angiogenesis suppression by siRNA via TLR3
Mark E. Kleinman et al.
Nature 452, 591–597
(3 April 2008); doi:10.1038/nature06765
| Summary | Full Text (HTML / PDF) |
news and views
RNA interference: Generic block on angiogenesis
Raghu Kalluri & Keizo Kanasaki
Nature 452, 543–545
(3 April 2008); doi:10.1038/452543a
| Full Text (HTML / PDF) |
letter
Dendritic cell PAR1–S1P3 signalling couples coagulation and inflammation
Frank Niessen et al.
Nature 452, 654–658
(3 April 2008); doi:10.1038/nature06663
| Summary | Full Text (HTML / PDF) |
article
Regulation of T cell survival through coronin-1-mediated generation of inositol-1,4,5-trisphosphate and calcium mobilization after T cell receptor triggering
Philipp Mueller et al.
Nature Immunology 9, 424–431
(April 2008); doi:10.1038/ni1570
| Summary | Full Text (HTML / PDF) |
article
Dual functions for the endoplasmic reticulum calcium sensors STIM1 and STIM2 in T cell activation and tolerance
Masatsugu Oh-hora et al.
Nature Immunology 9, 432–443
(April 2008); doi:10.1038/ni1574
| Summary | Full Text (HTML / PDF) |
review
How dying cells alert the immune system to danger
Hajime Kono & Kenneth L. Rock
Nature Reviews Immunology 8, 279–289
(April 2008); doi:10.1038/nri2215
| Summary | Full Text (HTML / PDF) |
letter
Interferon-γ is a therapeutic target molecule for prevention of postoperative adhesion formation
Hisashi Kosaka, Tomohiro Yoshimoto, Takayuki Yoshimoto, Jiro Fujimoto & Kenji Nakanishi
Nature Medicine 14, 437–441
(April 2008); doi:10.1038/nm1733
| Summary | Full Text (HTML / PDF) |
March
article
The E3 ubiquitin ligase Itch regulates expression of transcription factor Foxp3 and airway inflammation by enhancing the function of transcription factor TIEG1
K Venuprasad et al.
Nature Immunology 9, 245–253
(March 2008); doi:10.1038/ni1564
| Summary | Full Text (HTML / PDF) |
article
The E3 ligase Itch negatively regulates inflammatory signaling pathways by controlling the function of the ubiquitin-editing enzyme A20
Noula Shembade et al.
Nature Immunology 9, 254–262
(March 2008); doi:10.1038/ni1563
| Summary | Full Text (HTML / PDF) |
news and views
Itching to end NF-κB
Vigo Heissmeyer & Anjana Rao
Nature Immunology 9, 227–229
(March 2008); doi:10.1038/ni0308-227
| Full Text (HTML / PDF) |
review
IgE in allergy and asthma today
Hannah J. Gould & Brian J. Sutton
Nature Reviews Immunology 8, 205–217
(March 2008); doi:10.1038/nri2273
| Summary | Full Text (HTML / PDF) |
review
Toll-like receptors — taking an evolutionary approach
François Leulier & Bruno Lemaitre
Nature Reviews Genetics 9, 165–178
(March 2008); doi:10.1038/nrg2303
| Summary | Full Text (HTML / PDF) |
article
Translational control of the innate immune response through IRF-7
Rodney Colina et al.
Nature 452, 323–328
(20 March 2008); doi:10.1038/nature06730
| Summary | Full Text (HTML / PDF) |
letter
Memory CD4 T cells emerge from effector T-cell progenitors
Laurie E. Harrington, Karen M. Janowski, James R. Oliver, Allan J. Zajac & Casey T. Weaver
Nature 452, 356–360
(20 March 2008); doi:10.1038/nature06672
| Summary | Full Text (HTML / PDF) |
article
HIV-1 envelope protein binds to and signals through integrin α4β7, the gut mucosal homing receptor for peripheral T cells
James Arthos et al.
Nature Immunology 9, 301–309
(March 2008); doi:10.1038/ni1566
| Summary | Full Text (HTML / PDF) |
news and views
HIV's gut feeling
Quentin Sattentau
Nature Immunology 9, 225–227
(March 2008); doi:10.1038/ni0308-225
| Full Text (HTML / PDF) |
review
Interleukin 21: combination strategies for cancer therapy
Kresten Skak, Michael Kragh, Diana Hausman, Mark J. Smyth & Pallavur V. Sivakumar
Nature Reviews Drug Discovery 7, 231–240
(March 2008); doi:10.1038/nrd2482
| Summary | Full Text (HTML / PDF) |
letter
UNC93B1 delivers nucleotide-sensing toll-like receptors to endolysosomes
You-Me Kim, Melanie M. Brinkmann, Marie-Eve Paquet & Hidde L. Ploegh
Nature 452, 234–238
(13 March 2008); doi:10.1038/nature06726
| Summary | Full Text (HTML / PDF) |
article
T cell antigen receptor stimulation induces MALT1 paracaspase-mediated cleavage of the NF-κB inhibitor A20
Beatrice Coornaert et al.
Nature Immunology 9, 263–271
(March 2008); doi:10.1038/ni1561
| Summary | Full Text (HTML / PDF) |
article
The proteolytic activity of the paracaspase MALT1 is key in T cell activation
Fabien Rebeaud et al.
Nature Immunology 9, 272–281
(March 2008); doi:10.1038/ni1568
| Summary | Full Text (HTML / PDF) |
news and views
Finally, MALT1 is a protease!
Linda M McAllister-Lucas & Peter C Lucas
Nature Immunology 9, 231–233
(March 2008); doi:10.1038/ni0308-231
| Full Text (HTML / PDF) |
perspective
The molecular basis for public T-cell responses?
Vanessa Venturi, David A. Price, Daniel C. Douek & Miles P. Davenport
Nature Reviews Immunology 8, 231–238
(March 2008); doi:10.1038/nri2260
| Summary | Full Text (HTML / PDF) |
letter
The inflammasome recognizes cytosolic microbial and host DNA and triggers an innate immune response
Daniel A. Muruve et al.
Nature 452, 103–107
(6 March 2008); doi:10.1038/nature06664
| Summary | Full Text (HTML / PDF) |
article
Transcription factor KLF2 regulates the migration of naive T cells by restricting chemokine receptor expression patterns
Eric Sebzda, Zhiying Zou, John S Lee, Tao Wang & Mark L Kahn
Nature Immunology 9, 292–300
(March 2008); doi:10.1038/ni1565
| Summary | Full Text (HTML / PDF) |
news and views
Innocents abroad: regulating where naive T cells go
Barrett J Rollins
Nature Immunology 9, 233–235
(March 2008); doi:10.1038/ni0308-233
| Full Text (HTML / PDF) |
February
letter
Regulation of progenitor cell proliferation and granulocyte function by microRNA-223
Jonathan B. Johnnidis et al.
Nature 451, 1125–1129
(28 February 2008); doi:10.1038/nature06607
| Summary | Full Text (HTML / PDF) |
article
Smad3 and NFAT cooperate to induce Foxp3 expression through its enhancer
Yukiko Tone, Keiji Furuuchi, Yoshitsugu Kojima, Mark L Tykocinski, Mark I Greene & Masahide Tone
Nature Immunology 9, 194–202
(February 2008); doi:10.1038/ni1549
| Summary | Full Text (HTML / PDF) |
news and views
What turns on Foxp3?
Harald von Boehmer & Jens Nolting
Nature Immunology 9, 121–122
(February 2008); doi:10.1038/ni0208-121
| Full Text (HTML / PDF) |
article
Beta-catenin stabilization extends regulatory T cell survival and induces anergy in nonregulatory T cells
Yi Ding, Shiqian Shen, Andreia C Lino, Maria A Curotto de Lafaille & Juan J Lafaille
Nature Medicine 14, 162–169
(February 2008); doi:10.1038/nm1707
| Summary | Full Text (HTML / PDF) |
news and views
Safer, longer-lasting regulatory T cells with β-catenin
Jeffrey A Bluestone & Matthias Hebrok
Nature Medicine 14, 118–119
(February 2008); doi:10.1038/nm0208-118
| Summary | Full Text (HTML / PDF) |
review
Complement evasion by human pathogens
John D. Lambris, Daniel Ricklin & Brian V. Geisbrecht
Nature Reviews Microbiology 6, 132–142
(February 2008); doi:10.1038/nrmicro1824
| Summary | Full Text (HTML / PDF) |
article
Interleukin 17-producing T helper cells and interleukin 17 orchestrate autoreactive germinal center development in autoimmune BXD2 mice
Hui-Chen Hsu et al.
Nature Immunology 9, 166–175
(February 2008); doi:10.1038/ni1552
| Summary | Full Text (HTML / PDF) |
news and views
IL-17 drives germinal center B cells?
David Tarlinton
Nature Immunology 9, 124–126
(February 2008); doi:10.1038/ni0208-124
| Full Text (HTML / PDF) |
review
Micromanagement of the immune system by microRNAs
Harvey F. Lodish, Beiyan Zhou, Gwen Liu & Chang-Zheng Chen
Nature Reviews Immunology 8, 120–130
(February 2008); doi:10.1038/nri2252
| Summary | Full Text (HTML / PDF) |
letter
Co-option of a default secretory pathway for plant immune responses
Chian Kwon et al.
Nature 451, 835–840
(14 February 2008); doi:10.1038/nature06545
| Summary | Full Text (HTML / PDF) |
article
Transcription factor EBF restricts alternative lineage options and promotes B cell fate commitment independently of Pax5
Jagan M R Pongubala et al.
Nature Immunology 9, 203–215
(February 2008); doi:10.1038/ni1555
| Summary | Full Text (HTML / PDF) |
review
Of lineage and legacy: the development of mammalian hematopoietic stem cells
Elaine Dzierzak & Nancy A Speck
Nature Immunology 9, 129–136
(February 2008); doi:10.1038/ni1560
| Summary | Full Text (HTML / PDF) |
perpsective
The reverse stop-signal model for CTLA4 function
Christopher E. Rudd
Nature Reviews Immunology 8, 153–160
(February 2008); doi:10.1038/nri2253
| Summary | Full Text (HTML / PDF) |
review
Inter-kingdom signalling: communication between bacteria and their hosts
David T. Hughes & Vanessa Sperandio
Nature Reviews Microbiology 6, 111–120
(February 2008); doi:10.1038/nrmicro1836
| Summary | Full Text (HTML / PDF) |
letter
TANK-binding kinase-1 delineates innate and adaptive immune responses to DNA vaccines
Ken J. Ishii et al.
Nature 451, 725–729
(7 February 2008); doi:10.1038/nature06537
| Summary | Full Text (HTML / PDF) |
article
Acute upregulation of an NKG2D ligand promotes rapid reorganization of a local immune compartment with pleiotropic effects on carcinogenesis
Jessica Strid et al.
Nature Immunology 9, 146–154
(February 2008); doi:10.1038/ni1556
| Summary | Full Text (HTML / PDF) |
news and views
Stress gets under your skin
Daniel M Andrews & Mark J Smyth
Nature Immunology 9, 119–120
(February 2008); doi:10.1038/ni0208-119
| Full Text (HTML / PDF) |
review
Phagocytosis and comparative innate immunity: learning on the fly
Lynda M. Stuart & R. Alan Ezekowitz
Nature Reviews Immunology 8, 131–141
(February 2008); doi:10.1038/nri2240
| Summary | Full Text (HTML / PDF) |
brief communication
Switching constant domains enhances agonist activities of antibodies to a thrombopoietin receptor
Masayuki Kai et al.
Nature Biotechnology 26, 209–211
(February 2008); doi:10.1038/nbt1376
| Summary | Full Text (HTML / PDF) |
letter
NLRX1 is a regulator of mitochondrial antiviral immunity
Chris B. Moore et al.
Nature 451, 573–577
(31 January 2008); doi:10.1038/nature06501
| Summary | Full Text (HTML / PDF) |
article
'Tuning' of type I interferon-induced Jak–STAT1 signaling by calcium-dependent kinases in macrophages
Lu Wang et al.
Nature Immunology 9, 186–193
(February 2008); doi:10.1038/ni1548
| Summary | Full Text (HTML / PDF) |
article
Activated leukocyte cell adhesion molecule promotes leukocyte trafficking into the central nervous system
Romain Cayrol et al.
Nature Immunology 9, 137–145
(February 2008); doi:10.1038/ni1551
| Summary | Full Text (HTML / PDF) |
news and views
Lymphocyte transmigration in the brain: a new way of thinking
Boris P-L Lee & Beat A Imhof
Nature Immunology 9, 117–118
(February 2008); doi:10.1038/ni0208-117
| Full Text (HTML / PDF) |
January
article
Akirins are highly conserved nuclear proteins required for NF-κB-dependent gene expression in drosophila and mice
Akira Goto et al.
Nature Immunology 9, 97–104
(January 2008); doi:10.1038/ni1543
| Summary | Full Text (HTML / PDF) |
news and views
Akirins versus infection
Bruce Beutler & Eva Marie Y Moresco
Nature Immunology 9, 7–9
(January 2008); doi:10.1038/ni0108-7
| Full Text (HTML / PDF) |
perspective
How microorganisms tip the balance between interleukin-12 family members
Stanislas Goriely, Markus F. Neurath & Michel Goldman
Nature Reviews Immunology 8, 81–86
(January 2008); doi:10.1038/nri2225
| Summary | Full Text (HTML / PDF) |
article
Unique functions of the type II interleukin 4 receptor identified in mice lacking the interleukin 13 receptor α1 chain
Thirumalai R Ramalingam et al.
Nature Immunology 9, 25–33
(January 2008); doi:10.1038/ni1544
| Summary | Full Text (HTML / PDF) |
article
The contribution of transcription factor IRF1 to the interferon-γ–interleukin 12 signaling axis and TH1 versus TH-17 differentiation of CD4+ T cells
Shin-ichi Kano et al.
Nature Immunology 9, 34–41
(January 2008); doi:10.1038/ni1538
| Summary | Full Text (HTML / PDF) |
news and views
IRF1: a deus ex machina in TH1 differentiation
Derya Unutmaz & Jan Vilcek
Nature Immunology 9, 9–10
(January 2008); doi:10.1038/ni0108-9
| Full Text (HTML / PDF) |
review
Fcγ receptors as regulators of immune responses
Falk Nimmerjahn & Jeffrey V. Ravetch
Nature Reviews Immunology 8, 34–47
(January 2008); doi:10.1038/nri2206
| Summary | Full Text (HTML / PDF) |
article
The sphingosine 1-phosphate receptor 1 causes tissue retention by inhibiting the entry of peripheral tissue T lymphocytes into afferent lymphatics
Levi G Ledgerwood et al.
Nature Immunology 9, 42–53
(January 2008); doi:10.1038/ni1534
| Summary | Full Text (HTML / PDF) |
article
CD19 is essential for B cell activation by promoting B cell receptor–antigen microcluster formation in response to membrane-bound ligand
David Depoil et al.
Nature Immunology 9, 63–72
(January 2008); doi:10.1038/ni1547
| Summary | Full Text (HTML / PDF) |
article
Suppression of immunoglobulin E-mediated allergic responses by regulator of G protein signaling 13
Geetanjali Bansal, Zhihui Xie, Sudhir Rao, Karl H Nocka & Kirk M Druey
Nature Immunology 9, 73–80
(January 2008); doi:10.1038/ni1533
| Summary | Full Text (HTML / PDF) |
review
Launching the T-cell-lineage developmental programme
Ellen V. Rothenberg, Jonathan E. Moore & Mary A. Yui
Nature Reviews Immunology 8, 9–21
(January 2008); doi:10.1038/nri2232
| Summary | Full Text (HTML / PDF) |
article
Endothelin B receptor mediates the endothelial barrier to T cell homing to tumors and disables immune therapy
Ronald J Buckanovich et al.
Nature Medicine 14, 28–36
(January 2008); doi:10.1038/nm1699
| Summary | Full Text (HTML / PDF) |
news and views
Opening the gateway to tumors
Michael H Kershaw
Nature Medicine 14, 13–14
(January 2008); doi:10.1038/nm0108-13
| Summary | Full Text (HTML / PDF) |
review
From inflammation to sickness and depression: when the immune system subjugates the brain
Robert Dantzer, Jason C. O'Connor, Gregory G. Freund, Rodney W. Johnson & Keith W. Kelley
Nature Reviews Neuroscience 9, 46–56
(January 2008); doi:10.1038/nrn2297
| Summary | Full Text (HTML / PDF) |
review
An integrated model of the recognition of Candida albicans by the innate immune system
Mihai G. Netea, Gordon D. Brown, Bart Jan Kullberg & Neil A. R. Gow
Nature Reviews Microbiology 6, 67–78
(January 2008); doi:10.1038/nrmicro1815
| Summary | Full Text (HTML / PDF) |
article
Essential function for the calcium sensor STIM1 in mast cell activation and anaphylactic responses
Yoshihiro Baba, Keigo Nishida, Yoko Fujii, Toshio Hirano, Masaki Hikida & Tomohiro Kurosaki
Nature Immunology 9, 81–88
(January 2008); doi:10.1038/ni1546
| Summary | Full Text (HTML / PDF) |
article
Defective mast cell effector functions in mice lacking the CRACM1 pore subunit of store-operated calcium release-activated calcium channels
Monika Vig et al.
Nature Immunology 9, 89–96
(January 2008); doi:10.1038/ni1550
| Summary | Full Text (HTML / PDF) |
review
Immunological aspects of cancer chemotherapy
Laurence Zitvogel, Lionel Apetoh, François Ghiringhelli & Guido Kroemer
Nature Reviews Immunology 8, 59–73
(January 2008); doi:10.1038/nri2216
| Summary | Full Text (HTML / PDF) |
|
