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Introduction to the Signaling Gateway
Signal transduction discoveries are being made at an ever-increasing rate.
Tens of thousands of papers are published annually, which means that it is
almost impossible to keep up-to-date about individual cell signaling pathways,
let alone to maintain an overview of the field. The
Signaling Gateway, a comprehensive and free online resource
that is the result of a collaboration between the University of California
San Diego (UCSD) and Nature Publishing Group, aims to help you keep abreast
of these developments. The site is powered by the San Diego Supercomputer Center.
At the heart of this collaboration is the Molecule Pages,
a relational database of all significant published qualitative and quantitative
information on cell signaling proteins. This database will also allow entirely new
insights to be gleaned through intelligent data mining: the Molecule Pages database
was developed with the specific aim of allowing interactions, and indeed whole
pathways, to be modeled. Our goal is to filter the data to present only validated
information. Thus, invited experts will enter much of the data and every Molecule
Page will be comprehensively peer reviewed by Nature. We regard a Molecule Page as
a new full-fledged form of publication.
In addition, the Gateway is the home of Signaling Update,
which provides a one-stop overview of the latest and hottest research in cell
signaling for both the specialist and non-specialist alike. The Signaling Update
is updated weekly, presenting accessible digests of the current signaling literature
with links to primary research papers, as well as signaling-related news, jobs and
conference details. The Gateway also archives the Alliance for Cell Signaling (AfCS)
Data Center, a large public repository of primary
data gathered from the Alliance's cellular signaling experiments. The public is
welcome - indeed encouraged - to make use of these data in their own research
and publications.
This resource is made by the signaling community for the signaling community.
We actively encourage your contributions and feedback to ensure the success of this project.
To find out more about the Signaling Gateway, see the
special news feature
and 12-page supplement
in the 12 December issue of Nature, or the free article
Evolving Scholarly Communication in the
January 2004 issue of Learned Publishing. The Molecule Pages database is highlighted
in the 2008 Database Issue
of Nucleic Acids Research. Read additional articles about the Signaling Gateway
here.
The Signaling Gateway has won the Association of Learned and Professional
Society Publishers (ALPSP) Award for Publishing Innovation. This
international award is presented annually to products that display
'a significantly innovative approach to any aspect of publication'.
Read more about the award here.
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